United States Department of Veterans Affairs
United States Department of Veterans Affairs

Center for Imaging of Neurodegenerative Diseases

Michael W. Weiner, M.D.

 




Michael Weiner


Professor of Medicine, Radiology, and Psychiatry
University of California San Francisco
Director, MRS Unit
DVA Medical Center San Francisco


MRS Unit, 114M
VA Medical Center
4150 Clement St.
San Francisco, CA 94121

Tel: 415-750-2146
Fax: 415-668-2864
Email: Michael.Weiner@ucsf.edu




Education

The Johns Hopkins University, Baltimore, Maryland
B.A. 1961
SUNY Upstate Medical Center, Syracuse, New York

M.D. 1965

Intern & Assistant Resident in Medicine, Mt. Sinai Hospital, New York, New York

1965-1967

Clinical Fellow in Metabolism Yale-New Haven Medical Center, New Haven, Connecticut

1967-1968

Research Fellow (with Dr. Franklin H. Epstein) Yale University School of Medicine, New Haven, CT

1968-1970

University of Wisconsin, Institute for Enzyme Research, Madison, Wisconsin

1970-1972

Research Fellow (with Dr. Henry A. Lardy). Joint Appointment in Renal Section of the Department of Medicine (with Dr. Richard E. Rieselbach).

1970-1972



Honors
Honors in Organic Chemistry Research, The Johns Hopkins University
1961
Winner of an Honor Thesis Award SUNY Upstate Medical Center, Syracuse, NY
1965
Fellow of the National Kidney Foundation
1970-1972
Diplomate of the American Board of Internal Medicine in Internal Medicine and Nephrology
1972
Research Associate and Clinical Investigator of the Veterans Administration
1971-1977
Fellow of the American College of Physicians
1973
A. Blaine Brower Traveling Scholarship of the American College of Physicians (Laboratory of Sir Hans Krebs, Oxford, England)
1975
Young Investigator Award of the American College of Cardiology
1976
Mellon Fellowship for Stanford Junior Faculty Leave Program in the laboratories of Dr. Floyd C. Rector, Jr., U.C.S.F. and Dr. Frank Gotch
1978
Editor's Recognition Award with Special Distinction from Radiological Society of North America, Inc.
1993-1995
Fellow of the International Society for Magnetic Resonance in Medicine
2002
Council of National Institute of BioEngineering and BioImaging
2003


Professional Employment
Research and Education Associate of the Veterans Administration
1971-1974
Assistant Professor of Medicine, University of Wisconsin, School of Medicine
1971-1974
Assistant Professor of Institute for Enzyme Research, University of Wisconsin
1972-1974
Chief Metabolism Service, V.A. Hospital, Madison, Wisconsin
1973-1974
Clinical Investigator of the Veterans Administration
1974-1977
Assistant Professor of Medicine, Stanford University, School of Medicine
1974-1980
Assistant Chief of Artificial Kidney Center,
Palo Alto Veterans Administration Hospital, Palo Alto, CA
1974-1980
Associate Professor of Medicine in Residence,
University of California, San Francisco
1980-1990
Chief, Hemodialysis Unit,
San Francisco Veterans Administration Medical Center
1980-1983
Associate Professor of Radiology in Residence,
University of California, San Francisco
1983-1990
Scientific Director, Magnetic Resonance Unit,
San Francisco Veterans Administration Medical Center
1985
Associate Staff Member, Cardiovascular Research Institute
Senior Staff Member
1988-1993
1994
Bioengineering Graduate Group
University of California, Berkeley & San Francisco
1988
Graduate Group in Biophysics, University of California, Berkeley
1988
Professor of Medicine, Radiology, and Psychiatry
University of California, San Francisco
1990
Member, Alzheimer's Center Executive Committee
University of California, San Francisco
1994


Academic Activities
NIH study sections, site visits, and ad hoc review concerning
magnetic resonance spectroscopy
Editorial Board - Magnetic Resonance in Medicine
Editorial Board - NMR in Biomedicine
1988-2003
Editorial Board - Magnetic Resonance Imaging
Editorial Board - Journal of Magnetic Resonance Imaging
Editorial Advisory Board - MR, The Quarterly Magazine of Magnetic Resonance
Editorial Advisory Board – Journal of Neurochemistry
Review of manuscripts for many medical and scientific journals concerning magnetic resonance and nephrology
Co-organizer of Workshop on Techniques for In vivo NMR Spectroscopy.
       April 1987, San Francisco
       April 1989, San Francisco
       April 1990, San Francisco
       April 1991, St. Louis, MO
Co-organizer, 1st International Symposium on Magnetic Resonance Spectroscopy, Tokyo, Japan
1987
Magnetic Resonance Committee. American College of Radiology
1989-Present
Chairman, Committee on Magnetic Resonance Spectroscopy.
Society of Magnetic Resonance Imaging
1989-1990
Co-chairman, Symposium on Spectroscopy,
Society of Magnetic Resonance Imaging
1990
Chairman, Educational Symposium on Spectroscopy,
Society of Magnetic Resonance in Medicine
1990
Merit and Promotion Committee,
Department of Radiology, University of California, San Francisco

1995-1996

Chair of the Committee for Affiliated Sections-SMRT,
International Society for Magnetic Resonance in Medicine
1997-1998
Member, Faculty Development Committee, Department of Radiology,
University of California, San Francisco
1999- present
Scientific Advisory Board Member, Institute for the Study of Aging
2000
Co-organizer of the Alzheimer's Imaging Consortium, Washington, DC
July 2000
Chairman of the VA VISN Committee on Research
[This important committee concerns research throughout the VA network,
which includes all of Northern California, Reno, and Hawaii.]
1995-Present
Member, Scientific Advisory Board, Institute for the Study of Aging
2000-present
Council of National Institute of BioEngineering and BioImaging
2003


Public Service
Demonstrated Magnetic Resonance Unit to Colin Powell
1995
Demonstrated Magnetic Resonance Unit to Dr. George Rutherford, Chairman, Department of Veterans Affairs Realignment Advisory Committee
Dr. Weiner's band, "Giant Steps," played at the
DVA Medical Center Christmas Party.
1996


Societies

Sigma Xi

1971

American Federation of Clinical Research

1971

American Society of Nephrology

1971

International Society of Nephrology

1972

Mid-West Salt and Water Club

1972

American Heart Association Council on the Kidney in Cardiovascular Disease

1973

American Diabetes Association

1973

American Society of Artificial Internal Organs

1974

Biophysical Society

1975

American Association of University Professors

1975

The American Physiological Society

1975

American Society of Biological Chemists

1976

American Society for Pharmacology and Experimental Therapeutics

1977

Society for Experimental Biology and Medicine

1977

Western Society for Clinical Investigation

1978

International Society for Artificial Organs

1978

International Society of Magnetic Resonance

1983

Society of Magnetic Resonance in Medicine

1983

Bay Area Animal Resonance Club (Founder)

1984

Society of Magnetic Resonance Imaging

1985

American Association for the Advancement of Science

1985

Radiological Society of North America

1985

The New York Academy of Sciences

1987

Western Association of Physicians

1989




Bibliography



Thesis, Patent, and Book Chapters

  1. Weiner, M.W. A study of the effects of feeding a gallstone inducing diet on the concentrating ability of the mouse gall bladder in vitro. (Medical School Thesis).

  2. Hayslett, J.P., Kashgarian, M.I., Weiner, M.W., Epstein, F.H. Effects of changes of extracellular fluid on sodium reabsorption in the proximal and distal tubule. Chapter in Regulation of Body Fluid Volumes by the Kidney. pp.263-269, Eds: Cort, J.H., Lichardas, B., Karger, S. Basel, New York, 1970.

  3. Weiner, M.W., Epstein, F.H. Signs and symptoms of electrolyte disorders. Chapter 16 in Clinical Disorders of Fluid and Electrolyte metabolism, 2nd Edition. Eds: Maxwell, M.H., Kleeman, C.R. McGraw-Hill, Inc., New York, 1972.

  4. Weiner, M.W., Maffly, R.H. The provision of cellular metabolic energy for active ion transport. Chapter 16 in Physiological of Membrane Disorders. pp.287-314. Eds: Andreoli, T., Hoffman, J., Fanestil, D., Plenum Publishing Corporation, New York, 1978.

  5. Weiner, M.W. Special properties of kidney mitochondria. Chapter 2 in Biochemical Aspects of Kidney Function. p. 113, Eds: Ross, B.D., Guder, W.G., Pergamon Press, Oxford, 1980.

  6. Weiner, M.W. Use of uncoupling agents to investigate the regulation of active transport. Chapter 4 in Biochemical Aspects of Kidney Function. pp. 257-262. Eds: Ross, B.D., Guder, W.G. Pergamon Press, Oxford, 1980.

  7. Koretsky, A.P., Strauss, W., Basus, V., Murphy, J., Bendel, P., James, T., Weiner, M.W. Feasibility of 31P NMR to study metabolic effects of renal ischemia in vivo. Chapter 9 in Acute Renal Failure. pp. 42-46. Eds: Eliahu, H.E., Libby, J. 1982.

  8. Patent # 4,292,227 awarded on September 29, 1981 to Michaels, A.S., Weiner, M., Jalan, H. Stable supersaturated solutions of sparingly soluble salts.

  9. Koretsky, A.P., Weiner, M.W. 31Phosphorous magnetization transfer measurement of exchange reactions in vivo. Chapter 14 in Biomedical Magnetic Resonance. pp. 231-242. Eds: James, T.L., Margulis, A. Radiol. Res. Ed. Foundation, San Francisco, 1984.

  10. Adam, W., Weiner, M.W. Measurement of intracellular pH by 31P NMR: Relationship of pH to ammoniagenesis. Chapter in Contributions to Nephrology, Vol. 47, No. 3., Renal Ammonia Metabolism. Eds: Tannen, R.L., Schoolwerth, A.C., Kurokowa, K., Vinay, P. S. Karger, Basel, 1985.

  11. Weiner, M.W. Magnetic Resonance Imaging and Spectroscopy of the Kidney. Chapter in Current Nephrology, Vol. 9. Eds: Gonick, H. Year Book Medical Publications, Chicago, 1985.

  12. Matson, G.B., Weiner, M.W. MR spectroscopy in vivo:Principles, animal studies, and clinical applications. Chapter 11 in Magnetic Resonance Imaging. Eds: Bradley, W., Stark, D., Mosby, C.V. St. Louis, 1988.

  13. Matson, G.B., Weiner, M.W. Techniques and Application of in vivo Magnetic Resonance Spectroscopy. Proceedings of The San Francisco Workshop on Magnetic Resonance Spectroscopy In vivo. April 4-5, 1987. Chapters co-authored by M.W. Weiner:

    • Roth, K., Hubesch, B., Naruse, S., Gober, J., Lawry, T.J., Matson, G.B., Weiner, M.W. Quantitation of Metabolites in the Human Brain.

    • Matson, G.B., Twieg, D.B., Karczmar, G.S., Lawry, T.J., Gober, J., Valenzia, M., Boska, M.D., Weiner, M.W. Surface Coil 31P ISIS Experiments Applied to the Human Organs of Liver, Heart, and Transplanted Kidney.

    • Lawry, T.J., Matson, G.B., Weiner, M.W. Optimization of Two Coil Depth Pulse Experiments.

    • Karczmar, G.S., Lawry, T.J., Weiner, M.W., Matson, G.B. Computer Simulations of Tailored Excitation in the Rotating Frame.

    • Boska, M.D., Matson, G.B., Weiner, M.W. Evaluation and Comparison of RF Coil Decoupling Schemes.

    • Matson, G.B., Lawry, T.J., Weiner, M.W. Optimization of Surface Coil Size through Computer Modeling.

    • Roth, K., Weiner, M.W. Computer Simulations of Reactions Involving High-Energy Phosphates.

  14. Weiner, M.W. Clinical applications of magnetic resonance spectroscopy and spectroscopic imaging. Chapter in Diagnostic Radiology. pp. 137-146. Eds: Margulis, A.R., Gooding, C.A. Radiology Research Education Foundation, San Francisco, 1988.

  15. Karczmar, G.S., Weiner, M.W. Investigation of metabolic disorders in patients and animal models using in vivonuclear magnetic resonance spectroscopy. Chapter in Cell Function and Disease. Eds: Todd, L.E., Ca񥤯, L.E. Plenum Press, 1988.

  16. Meyerhoff, D.J., Weiner, M.W. Magnetic resonance spectroscopy. Chapter in Alimentary Tract Radiology, 4th Edition, Vol. 2. Ed: Margulis, A. The C.V. Mosby Co., St. Louis, 1988.

  17. Weiner, M., Schaefer, S., Meyerhoff, D., Hubesch, B., Karczmar, G, Boska, M., Twieg, D., Matson, G. Clinical Uses of Magnetic Resonance Spectroscopy. Chapter in Diagnostic Radiology. Eds: Gooding, C., Margulis, A. Radiology Research and Education Foundation, San Francisco, 1989.

  18. Schaefer, S., Massie, B., Weiner, M. Magnetic Resonance Spectroscopy of the Heart. Chapter in Cardiology Clinics. Eds: Wolfe, C., Saunders, W.B. 1988.

  19. Schaefer, S., Weiner, M.W., and Massie, B. Clinical applications of cardiac spectroscopy. Chapter 19 in Cardiac Imaging - A Companion to Braunwald's Heart Disease. pp. 967-976. Eds: Marcus, M.L., Schelbert, H., Skorton, D., Wolf, G.L. W.B. Saunders Co., 1991.

  20. Weiner, M.W. Clinical potential of magnetic resonance spectroscopy and spectroscopic imaging. Chapter in Diagnostic Radiology. pp. 515-524. Ed: Gooding, C.A. Radiology Research and Education Foundation, University of California, San Francisco, 1989.

  21. Weiner, M.W., Baker, A., Carson, P., Schaefer, S., Schwartz, G., DeGroot, M., Massie, B., Miller, R.G. 31P MRS studies of skeletal muscle and heart: evidence of metabolic regulation by inorganic phosphate. Chapter 8 in Noninvasive Techniques in Biology and Medicine. pp.111-124. Eds: Freeman, S.E., Fukushima, I., Greene, E.R. San Francisco Press, Inc., San Francisco, 1990.

  22. Karczmar, G.S., Meyerhoff, D.J., Hubesch, B., Boska, M.D., Valone, F., Twieg, D.B., Wilkinson, M., Matson, G.B., Weiner, M.W. Preliminary 31P MR studies of human tumors. Chapter in Magnetic Resonance in Experimental and Clinical Oncology. pp. 271 ? 292. Eds: Evelhoch, J.L., Negendank, W., Valeriote, F.A., Baker, L.H. Kluwer Academic Publications, Boston, 1990.

  23. Meyerhoff, D.J., Weiner, M.W. Magnetic resonance spectroscopy of the liver: A review. Chapter X in Liver Imaging - Present and Future Trends in MRI, CT, and Ultrasound. p. 289. Eds: Stark, D., Ferucci, J. Andover Medical Publishers, Boston, 1990.

  24. Weiner, M.W. Forward In NMR for Physicians and Biologists. Eds: Hausser, K.H., Kalbitzer, H.R. Springer-Verlag, 1991.

  25. Schwartz, G.G., Weiner, M.W. Magnetic resonance spectroscopy: Basic principles and potential applications in the study of the cardiovascular system. Chapter in Cardiovascular Magnetic Resonance Spectroscopy. Eds: Schaefer, S., Balaban, R. Kluwer Academic Publications, 1991.

  26. Figueredo, V.M., Weiner, M.W. Magnetic resonance of the heart. Chapter in Clinical Applications of Magnetic Resonance Spectroscopy. Ed: Narusa, S. Igaku-Shoin LTD, Tokyo, 1991.

  27. Meyerhoff, D.J., Weiner, M.W. Clinical application of magnetic resonance spectroscopy to renal disease. Chapter in Clinical Applications of Magnetic Resonance Spectroscopy. Ed: Narusa, S. Igaku-Shoin LTD, Tokyo, 1991.

  28. Deicken, R.F., Calabrese, G., Meyerhoff, D.J., Sappey-Marinier, D., Fein, G., Weiner, M.W. Magnetic resonance spectroscopy of the human brain in neuropsychiatric disorders. Chapter in Biological Psychiatry. Eds: Racagni, G., Brunello, N., Fukuda, T. Excerpta Medica, New York, 1991.

  29. Meyerhoff, D.J., Mackay, S., Baker, A.J., Schaefer, S., and Weiner, M.W. Magnetic Resonance Spectroscopy. Chapter in Magnetic Resonance Imaging of the Body, Second Edition. Eds: Higgins, C.B., Hricak, H., Helms, C.A. Raven Press, New York, 1992.

  30. Meyerhoff, D.J., Weiner, M.W. Clinical 31P magnetic resonance spectroscopy of cancers. In Proceedings ART91, International Symposium of the V. Vaillant Foundation: Tumor Response Monitoring and Treatment Planning.

  31. Matson, G.B., Weiner, M.W. Spectroscopy. Chapter 15 in Magnetic Resonance Imaging. Eds: Stark, D.D., Bradley Jr., W.G. Mosby-Year Book, St. Louis, 1992.

  32. Meyerhoff, D.J., Hetherington, H.P., Hugg, J.W., Matson, G.B., Fein, G., Maudsley, A.A., Weiner, M.W. Magnetic resonance spectroscopy and spectroscopic imaging of human liver, heart, kidney, and brain. Chapter in Imaging in alcohol Research. pp.177-193 Eds: Zakhari, S., Witt, E. U.S. Department of Health and Human Services, Rockville, MD, 1992.

  33. Weiner, M.W. Clinical Spectroscopy. Chapter in Clinical MR Refresher Course, Basic Magnetic Resonance Spectroscopy, Advanced Magnetic Resonance Spectroscopy. pp. 47-55. Society of Magnetic Resonance in Medicine, Twelfth Annual Scientific Meeting, New York, 1993.

  34. Hugg, J.W., Laxer, K.D., Weiner, M.W. Focal epilepsy localization by magnetic resonance spectroscopic imaging. Chapter in Advances in Clinical Neuroscience, Vol. 3. pp. 011-026. Ed: Sinha, K.K., 1993.

  35. Kent-Braun, J.A., Miller, R.G., Weiner, M.W. Magnetic resonance spectroscopy studies of human muscle. Chapter in Radiology Clinic of North America, Vol. 32, No. 2. pp. 313-335 Ed: Sartoris, D.J., Saunders, W.B. Company, 1994.

  36. Fein, G., Meyerhoff, D.J., Scianfani, V.D., Ezekiel, F., Poole, N., MacKay, S., Dillon, W.P., Constans, J-M., Weiner, M.W. 1H MRSI separates neuronal from glial changes in alcohol-related brain atrophy. Chapter in Alcohol and Glial Cells, Vol. 12. pp. 227-241. Ed: Lancaster, F. NIAAA, 1994.

  37. Fein, G., Meyerhoff, D.J., Di Sclafani, V., Ezekiel, F., Poole, N., MacKay, S., Dillon, W.P., Constans, J.M., Weiner, M.W. 1H magnetic resonance spectroscopic imaging separates neuronal from glial changes in alcohol-related brain atropy. Chapter in NIAAA Research Monograph - 27, Alcohol and Glial Cells. Ed: Lancaster, F.E. 1994.

  38. Laxer, K.D., Hugg, J.W., Matson, G.B., and Weiner, M.W.: Application of Spectroscopy to Epilepsy. Chapter in Magnetic Resonance Scanning and Epilepsy. pp. 199-201. Ed: Shorvon, S.D., et al. Plenum Press, New York, 1994.

  39. Kent-Braun, J.A., Miller, R.G., Weiner, M.W. Human skeletal muscle metabolism in health and disease: Utility of magnetic resonance spectroscopy. Chapter 10 in Exercise and Sport Sciences Reviews. pp. 305-347. Ed: Holloszy, J.O. Williams and Wilkins, 1995.

  40. Figueredo, V.M., Weiner, M.W. MRS of the heart. Chapter in Clinical Applications of Magnetic Resonance Spectroscopy. Ed: Naruse, S. Igaku-Shoin Ltd., Tokyo, Japan, 1995.

  41. Meyerhoff, D.J., Weiner, M.W. Clinical application of MRS to renal disease. Chapter in Clinical Applications of Magnetic Resonance Spectroscopy. Ed: Naruse, S. Igaku-Shoin Ltd., Tokyo, Japan, 1995.

  42. Miller, R.G., Kent-Braun, J.A., Sharma, K.R, Weiner, M.W. Mechanisms of human muscle fatigue: quantitating the contribution of metabolic factors and activation impairment. pp.195-210. Ed: Gandevia, S.C. Fatigue, Plenum Press, 1995.

  43. Miller, R.G., Kent-Braun, J.A., Weiner, M.W. Techniques for quantifying central and periopheral factors in fatigue. Chapter in Recent Advances in Clinical Neurophysiology. Eds: Kimura, J., Shibasaki, H. Elsevier, Tokyo, Japan, 1996.

  44. Weiner, M.W. Kidney, prostate, testicle, and uterus MRS of humans. Chapter in Encyclopedia of NMR. Eds: Grant, D.M., Harris, R.K. John Wiley & Sons, Ltd., 1996.

  45. Meyerhoff, D.J., Kent-Braun, J.A., Greyson, C., Weiner, M.W. Clinical applications of magnetic resonance spectroscopy and spectroscopic imaging. Chapter in Magnetic Resonance Imaging of the Body, Third Edition. Eds: Higgins, C.B., Hricak, H., Helms, C.A. Lippincott Raven Press, New York, 1997.

  46. Weiner, M.W. Magnetic resonance spectroscopy of cardiac and skeletal muscle. Chapter in ISMRM Educational Course Syllabus. pp.298-320. International Society for Magnetic Resonance in Medicine, Fifth Scientific Meeting, Vancouver, Canada, 1997.

  47. Weiner, M.W. Magnetic resonance spectroscopy of brain in neurodegenerative disease. Chapter in ISMRM Educational Course Syllabus. pp.337-369. International Society for Magnetic Resonance in Medicine, Fifth Scientific Meeting, Vancouver, Canada, 1997.

  48. Weiner, M.W. Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) of Alzheimer?s disease. Chapter in Alzheimer?s Disease II. pp.121-125. Eds: Friedman, E., Savage, L. IBC Library Series, Southborough, MA, 1997.

  49. Matson, G.B., Govindaraju, V., Kiefer, A.P., Schuff, N., Weiner, M.W., Maudsley, A.A. Multiple-echo proton spectroscopic imaging of human brain. Chapter in High-Power Gradient MR-Imaging: Advances in MRI II. pp.239-244. Eds: Oudkerk, M., Edelman, R.R. Blackwell Wissenschaft, Berlin, 1997.

  50. Vermathen, P., Laxer, K.D., El Din, M., Matson, G.B., Weiner, M.W. 1H MRSI of the hippocampus in epilepsy patients and in controls. Chapter in High-Power Gradient MR-Imaging: Advances in MRI II. pp.249-252. Eds: Oudkerk, M., Edelman, R.R. Blackwell Wissenschaft, Berlin, 1997.

  51. Weiner, M.W.: Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Spectroscopic Imaging (MRSI): Technical Developments and Clinical Applications. Chapter in High-Power Gradient MR-Imaging: Advances in MRI II. Editors: M. Oudkerk, R.R. Edelman, Blackwell Wissenschaft, Berlin, pp.199-202, 1997.

  52. Meyerhoff, D.J., Fein, G., Weiner, M.W. Cerebral metabolic effects of HIV infection studied by 1H MR spectroscopic imaging. Chapter in High-Power Gradient MR-Imaging: Advances in MRI II. pp.245-248. Eds: Oudkerk, M., Edelman, R.R. Blackwell Wissenschaft, Berlin, 1997.

  53. Schwartz, G.G., Greyson, C.R., Massie, B.M., Weiner, M.W., Wisneski, J.A. Energy metabolism of the right ventricle. Chapter in Current and Future Applications of Magnetic Resonance in Cardiovascular Disease. pp. 475-491. Eds: Higgins, C.B., Ugurbil, K. American Heart Association/Futura Medical Publishers, Armond, NY, 1998.

  54. Schuff, N., Sappey-Marinier, D., Weiner, M.W. Magnetic Resonance Spectroscopy in Dementia. Chapter in Neuroimaging of Normal Aging in and Uncommon Causes of Dementia; Current Issues in Neurodegenerative Diseases, Vol. 7, pp.225-244. Eds: Fazekas, Schmidt, Alavi. ICG Publications, The Netherlands, 1998.

  55. Sappey-Marinier, D., Schuff, N., Weiner, M.W. Magnetic Resonance Spectroscopy of Normal Brain in Maturation and Aging. Chapter in Neuroimaging of Normal Aging in and Uncommon Causes of Dementia; Current Issues in Neurodegenerative Diseases, Vol. 7. Eds: Fazekas, Schmidt, Alavi. ICG Publications, The Netherlands, 1998.

  56. Matson, G.B., Weiner, M.W. Spectroscopy. Chapter in Magnetic Resonance Imaging, Third Edition. pp.181-214. Eds: Stark, D.D., Bradley, Jr., W.G. Mosby-Year Book, St. Louis, 1998.

  57. Weiner, M.W., Maudsley, A.A., Schuff, N., Soher, B.J., Vermathen, P., Fein, G., Laxer, K. Multislice 1H Magnetic Resonance Spectroscopic Imaging: Assessment of Epilepsy, Alzheimer's Disease, and Amyotrophic Lateral Sclerosis. International Society for Optical Engineering. Chapter in Medical Imaging 1998: Physiology and Function from Multidimensional Images. Vol. 3337. pp. 203-209. Ed: Hoffman, E.A. SPIE, San Diego, 1998.

  58. Schuff, N., Vermathen, P., Maudsley, A.A., Weiner, M.W. Proton Magnetic Resonance Spectroscopic Imaging in Neurodegenerative Diseases, Chapter in Current Science, Vol. 6. pp. 800-807, 1998, and Vol XX. Indian Academy of Sciences Publication, 1999.

  59. Weiner, M.W. Kidney, Prostrate, Testicle and Uterus of Subjects studied by MRS. Chapter in Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy. Ed: Young, I. Wiley, 2000.

  60. Schuff, N., Du, A.T., Amend, D., Hsu, Y.Y., Laakso, M.P., Jagust, W., Chui, H.C., Weiner, M.W. MRI of Entorhinal Cortex and Hippocampus in Alzheimer?s Disease, Subcortical Ischemic Vascular Dementia and Mixed Dementia. Chapter in Alzheimer?s Disease: Advances in Etiology, Pathogenesis, and Therapeutics. pp. 229-236. Eds: Iqbal, K., Sisodia, S.S., Winblad, B. John Wiley & Sons, Ltd., London, 2001.

  61. Chui, H., Fein, G., Mungas, D., Jagust, W., Weiner, M., Vinters, H. Neuroimaging and Pathological Correlates of Dementia Associated with Subcortical Ischemic Vascular Disease (SIVD). Chapter in Contemporary Neuropsychiatry. pp. 147-151. Eds: Miyoshi, K., Shapiro, C.M., Gaviria, M., Morita, Y. Springer-Verlag, Hong Kong, Tokyo, 2001.



Journal Publications

  1. Tepperman, J., Weiner, M.W.? Experimental gallstones: An adventure in biological geology.? Yale J. Biol. Med., 41:107-119, 1968.

  2. Weiner, M.W., Epstein, F.H.? Signs and symptoms of electrolyte disorders.? Yale J. Biol. Med., 43:76-104, 1970.

  3. Weiner, M.W., Weinman, E.J., Kashgarian, M., Hayslett, J.P.? Accelerated reabsorption in the proximal tubule produced by volume depletion.? J. Clin. Invest., 50:1379-1385, 1971.

  4. Weiner, M.W., Torretti, J., Sauer, L.A., Epstein, F.H.? Renal mitochondrial enzymes in potassium depletion.? Amer. J. Physiol., 221:613-617, 1971.

  5. Cunarro, J.A., Weiner, M.W.? Quantitative correlation between the proton carrying and respiratory-stimulating properties of uncoupling agents using rat liver mitochondria.? Nature, 245:36-37, 1973.

  6. Weiner, M.W., Lardy, H.A.? Reduction of pyridine nucleotides by adenosinediphosphate in kidney mitochondria: Effects of sodium, magnesium and inhibitors of oxidative phosphorylation.? J. Biol. Chem., 248:7682-7687, 1973.

  7. Manuel, M.A., Beirne, G.J., Wagnild, J.P., Weiner, M.W.? An effect of spironolactone on urinary acidification in normal man.? Arch. Intern. Med., 134:472-474, 1974.

  8. Cunarro, J., Weiner, M.W.? Comparison of four methods for measuring urinary ammonia.? Kidney International, 5:303-305, 1974.

  9. Weiner, M.W., Lardy, H.A.: Effects of respiratory chain inhibitors on mitochondrial ATPase activity.? Arch. Biochem. Biophys., 162:568-577, 1974.

  10. Weiner, M.W.? ATPase activity of kidney mitochondria stimulated by sodium.? Amer. J. Physiol., 228:815-820, 1975.

  11. Weiner, M.W.? Mitochondrial permeability to chloride ion.? Amer. J. Physiol., 228:122-126, 1975.

  12. Cunarro, J.A., Johnson, W.A., Uehling, D.T., Updike, S.J., Weiner, M.W.? Effects of low temperature preservation on metabolite levels of dog renal cortex.? Proceedings of the Clinical Dialysis and Transplant Forum IV:196-200, 1974.

  13. Cunarro, J.A., Weiner, M.W.? Mechanism of action of agents which uncouple oxidative phosphorylation: Direct correlation between proton carrying and respiratory-releasing properties using rat liver mitochondria.? Biochem. Biophys. Acta., 387:234-240, 1975.

  14. Wingert, K.J., Weiner, M.W.? Acetate dislysance by the Dow-4 and Gambro 13.5 artificial kidneys.? Proceedings of the Clinical Dialysis and Transplant Forum V:122-127, 1975.

  15. Manuel, M.A., Weiner, M.W.? Effects of ethacrynic acid and furosemide on isolated rat kidney mitochondria: Inhibition of electron transport in the region of phosphorylation site II.? J. Pharmacol. Exp. Ther., 198:209-221, 1976.

  16. Cunarro, J.A., Johnson, M.A., Uehling, D.T., Updike, S.J., Weiner, M.W.? Metabolic consequences of low temperature kidney preservation.? J. Lab. Clin. Med., 88:873-884, 1976.

  17. Richards, R.H., Dowling, J.A., Vreman, H.J., Feldman, C.A., Weiner, M.W.? Acetate levels in human plasma.? Proceedings of the Clinical Dialysis and Transplant Forum V1:73-79, 1976.

  18. Manuel, M.A., Weiner, M.W.? Effects of ethacrynic acid and furosemide on phosphorylation reactions of kidney mitochondria: Inhibition of the adenine nucleotide translocase.? Biochem. Biophys. Acta., 460:445-454, 1977.

  19. Soboslai, G., McTigue, M., Weiner, M.W.? Mechanism of active chloride transport by the urinary bladder of the Colombian toad.? Amer. J. Physiol., 233:F421-F427, 1977.

  20. Diamond, A., Weiner, M.W.? Renal hydrogen ion secretion and excretion during acute acid loading.? Mount Sinai Journal of medicine, 45:342-356, 1978.

  21. Weiner, M.W.? Effects of halothane on mitochondrial ion permeability.? Pharmcol. Res. Comm., 10:31-42, 1978.

  22. Cunarro, J.A., Weiner, M.W.? Effects of ethacrynic acid and furosemide on respiration of isolated kidney tubules: The role of ion transport and the source of metabolic energy.? J. Pharmacol. Exp. Ther., 206:198-206, 1978.

  23. Weiner, M.W.? Effects of chloride, nitrate and sulfate on ATPase of renal cortex and medulla.? Proc. Soc. Exper. Biol. Med., 158:370-372, 1978.

  24. Vreman, J.H., Dowling, J.A. Raubach, R.A., Weiner, M.W.? Determination of acetate in biological material by vacuum microdistillation and gas chromatography.? Anal. Chem., 50:1138-1141, 1978.

  25. Crawford, D.R., Reyna, R.S., Weiner, M.W.? Effects of in vivo and in vitro dialysis on plasma transaminase activity.? Nephron, 22:418-422, 1978.

  26. Johnson, W.A., Weiner, M.W.? Protective effects of ketogenic diets on signs of hypoglycemia.? Diabetes, 27:1087-1091, 1978.

  27. Weiner, M.W.? Uncoupling agents distinguish between the effects of metabolic inhibitors and transport inhibitors.? Science, 204:187-188, 1979.

  28. Assomull, V., Vreman, H., and Weiner, M.W.? Mass balance of base equivalents during hemodialysis: Importance of organic acid ions.? Proceedings of the Clinical Dialysis and Transplant Forum, 8:137-141, 1978.

  29. Wingert, K.J., Weiner, M.W.? Acetate transfer across membranes of artificial kidneys in vitro.? Kidney International, 15:593-600, 1979.

  30. Tollinger, C.D., Vreman, H.J., Weiner, M.W.? Measurement of acetate in human blood by gas chromatography: Effects of sample preparation, feeding and various diseases.? Clinical Chemistry, 25:1787-1790, 1979.

  31. Urion, D., Vreman, H.J., Weiner, M.W.? Effects of acetate on hypoglycemic seizures in mice.? Diabetes, 28:1022-1026, 1979.

  32. Assomull, V.M., Vreman, J.H., Weiner, M.W.? Evidence that acetate in dialysis does not stimulate lipid synthesis.? Proceedings of the Clinical Dialysis and Transplant Forum IX:73-79, 1979.

  33. Kaiser, B.A., Assomull, V.M., Vreman, H.J., Weiner, M.W.? Dialysance of acetate and bicarbonate: Effect of ultrafiltration.? Proceedings of the Clinical Dialysis and Transplant Forum IX:104-107, 1979.

  34. Vreman, H.J., Thorning, D., Weiner, M.W.? Effects of dietary acetate and bicarbonate on experimental atherosclerosis in rabbits.? Atherosclerosis, 35:145153, 1980.

  35. Weiner, M.W.? The use of an uncoupling agent to investigate the regulation ofactive sodium transport.? Int. J. Biochem., 12:257-261, 1980.

  36. Weiner, M.W.? Special properties of kidney mitochondria.? Int. J. Biochem., 12:113-117, 1980.

  37. Weiner, M.W.? The effects of bicarbonate and hydroxyl ions on chloride transport by toad bladders.? Biochim. Biophys. Acta., 596:292-301, 1980.

  38. Winder, C.L., Weiner, M.W.? Effects of metabolic and transport inhibitors on sodium transport and C02 production of toad bladders: Use of an uncoupling agent to distinguish between effects on transport and metabolism.? J. Pharmacol. Exp. Ther., 213:375-382, 1980.

  39. Weiner, M.W.? Effects of furosemide and ethacrynic acid on sodium transport and CO2 production of toad bladders: Evidence for direct inhibition of active transport.? J. Pharmacol. Exp. Ther., 213:383-389, 1980.

  40. Weiner, M.W.? Effects of sodium and potassium on energy metabolism and sodium transport of toad bladders. ?J. Pharmacol. Exp. Ther., 213:390-394, 1980.

  41. Levi, J., Jacobs, C., Kalman, S., McTigue, M., Weiner, M.W.? Mechanism of cis-platinum nephrotoxicity: I. Effects of sulfhydryl groups in rat kidneys.? J. Pharmacol. Exp. Ther., 213:545-550, 1980.

  42. Dobyan, D.C., Levi, J., Jacobs, C., Kosek, J., Weiner, M.W.? Mechanism of cis-platinum nephrotoxicity: II Morphologic observations.? J. Pharmacol. Exp. Ther., 213:551-556, 1980.

  43. Spires, D.A., Weiner, M.W.? Use of an uncoupling agent to distinguish between direct stimulation of metabolism and direct stimulation of transport: Investigation of antidiuretic hormone and aldosterone.? J. Pharmacol Exp. Ther., 214:507-515, 1980.

  44. Weiner, M.W., Greene, K., Vreman, H., Wemmer, D., Jardetsky, N.W., Jardetsky, 0.? NMR measurements of metabolites in organs of live animals using chronically implanted radiofrequency coils.? IRCS Medical Science, 8:671, 1980.

  45. Jacobs, C., Kalman, S.M., Tretton, M., and Weiner, M.W.? Renal handling of cis-diamminedichloroplatinum (II).? Cancer Treatment Reports, 64:1223-1226, 1980.

  46. Vreman, H.J., Assomull, V.M., Kaiser, B.A., Blaschke, T.F., Weiner, M.W.? Acetate metabolism and acid-base homeostasis during hemodialysis: Influence of dialyzer efficiency and rate of acetate metabolism.? Kidney Intl., 18:(Supplement 10) S62-S74, 1980.

  47. Vreman, H.J., Venter, C., Leegwater, J., Oliver, C., Weiner, M.W.? Taste, smell and zinc metabolism in patients with chronic renal failure.? Nephron, 26:163-170, 1980.

  48. Kaiser, B.A., Potter, D.E., Bryant, R.E., Vreman, H.J., Weiner, M.W.? Acid-base changes and acetate metabolism during routine and high efficiency hemodialysis in children.? Kidney Intl., 19:70-79, 1981.

  49. Richards, R.H., Vreman, H.J., Zager, P., Feldman, C., Blaschke, T., Weiner, M.W.? Acetate metabolism in normal human subjects.? Am. J. Kid. Diseases, 11:47-57, 1982.

  50. Cunarro, J.A., Schultz, S.E., Johnson, W.A., Weiner, M.W.? Effects of ischemia on metabolite concentrations in dog renal cortex.? Renal Physiol. Basel, 5:143-155, 1982.

  51. Weiner, M.W., Jacobs, C. ?Mechanism of cisplatin nephrotoxicity.? Fed. Proc., 42:2974-2978, 1983.

  52. Weiner, M.W.? Acetate metabolism during hemodialysis.? Artificial Organs, 6:370-377, 1982.

  53. Weiner, M.W.? Acetate dialysate vs. bicarbonate dialysate.? Trans. Amer. Soc. of Artificial Internal Organs, 28:661-662, 1982.

  54. McTigue, M., Ting, G.O., Weiner, M.W.? Relationship between sodium transport and oxygen consumption in the isolated perfused rat kidney.? Renal Physiology, 6:112-129,1983.

  55. Karczmar, G.S., Koretsky, A.P., Bisssell, M.J., Klein, M.P., Weiner, M.W.? A device for maintaining viable cells at high densities for NMR studies.? J. Magn. Res., 53:123-128, 1983.

  56. Koretsky, A.P., Wang, S., Murphy-Boesch, J., Klein, M.P., James, T.L., Weiner, M.W.? 31P NMR spectroscopy of rat organs, in situ, using chronically implanted radiofrequency coils.? Proc. Nat. Acad. Sci. U.S.A., 80:7491-7495, 1983.

  57. Geiser, M.T., Van Dyke, C., East, R., Weiner, M.W.? Psychological reactions to continuous ambulatory peritoneal dialysis.? Intl. J. Psych. Med., 13:299-307, 1984.

  58. Gonzalez-Mendez, R., Litt, L., Koretsky, A.P., Von Golditz, J., Weiner, M.W., James, T.L.? Comparison of 31P NMR spectra of in vivorat brain using convolution difference and saturation with a surface coil: Source of the broad component in the brain spectrum.? J. Mag. Reson., 57:526-533 1984.

  59. Weiner, M.W., Adam, W.R.? Magnetic Resonance Spectroscopy for evaluation of renal function.? Seminars in Urology, 3:34-42, 1985.

  60. Koretsky, A.P., Basus, J.V., James, T.L., Klein, M.P., Weiner, M.W.? Detection of exchange reactions involving small metabolite pools using NMR magnetization transfer techniques: relevence to subcellular compartmentation of creatine kinase.? Mag. Res. Med., 2:586-594, 1985.

  61. Koretsky, A.P., Wang, S., Klein, M.P., James, T.L., Weiner, M.W.? 31P NMR saturation transfer measurements of phosphorus exchange reactions in rat heart and kidney in situ.? Biochem., 25:77-84, 1986.

  62. Karczmar, G.S., Weiner, M.W.? A single acquisition localization technique.? Mag. Res. Med., 3:341-345, 1986.

  63. Weiner, M.W.? Magnetic resonance measurements of renal metabolism, structure, and function.? Seminars in Nephrology, 6:139-152, 1986.

  64. Adam, W.R., Koretsky, A.P., Weiner, M.W.? Measurement of renal intracellular pH in rats in vivousing 31P NMR: ?Effects of acidosis and K depletion.? Am. J. Physiol., 251:F904-F910, 1986.

  65. Shine, N.R., Xuan, J.A., Koretsky, A.P., Weiner, M.W.? Determination of renal molar concentrations of phosphorous containing metabolites in vivousing 31P NMR.? Mag. Reson. Med., 4:244-251, 1987.

  66. Weiner, M.W.? NMR spectroscopy for clinical medicine animal models and clinical examples.? Ann. N.Y. Acad. Sci., 508:287-299, 1987.?

  67. Shine, N.R., Adam, W.P., Xuan, J.A., Weiner, M.W.? NMR Studies of renal metabolism: regulation of renal function by ATP and pH.? Ann. N.Y. Acad. Sci., 508:99-108, 1987.?

  68. Weiner, M.W.? Investigation of cardiac ischemia and tumor therapy with magnetic resonance spectroscopy.? Proceedings of Internationales Kernspintornographie Symposium Garmisch Partenkirchen. pp. 331-334.? Ed: Lissner, J., 1987.

  69. Miller, R.G., Giannini, D., Milner-Brown, H.S., Layzer, R.B., Koretsky, A.P., Hooper, D., Weiner, M.W.? Effects of fatiguing exercise on high-energy phosphates, force, and EMG: Evidence for 3 phases of recovery.? Muscle & Nerve, 10:810-821, 1987.

  70. Karczmar, G.S., Weiner, M.W., Matson, G.B.? Detection of residual z magnetization: application to the surface coil rotating frame experiment.? Magn. Reson. Med., 71:360-364, 1987.

  71. Adam, W.R., Koretsky, A.P., Weiner, M.W.? Measurement of tissue potassium in vivousing 39K nuclear magnetic resonance.? Biophys. J., 51:265-271, 1987.

  72. Vink, R., McIntosh, T., Weiner, M.W., Faden, A.I.? Effects of traumatic brain injury on cerebral high-energy phosphates and pH.? J. Cereb. Blood Flow, 7:563-571, 1987.

  73. Vink, R., McIntosh, T.K., Fernyak, S.E., Weiner, M.W., Faden, A.I.? Proton and phosphorus NMR studies of traumatic brain injury in rats.? Ann. N.Y. Acad. Sci., 508:497-500, 1987.

  74. Karczmar, G.S., Lawry, T.J., Weiner, M.W., Matson, G.B.? Shaped pulses for slice selection in the rotating frame - a study using computer simulations.? J. Magn. Reson., 76:41-53, 1988.

  75. Vink, R., McIntosh, T.K., Demediuk, P., Weiner, M.W., Faden A.I.? Decline in intracellular free Mg2+ is associated with irreversible tissue injury after brain trauma.? J. Biol. Chem., 263:757-761, 1988.

  76. Adam, W.R., Koretsky, A.P., Weiner, M.W.? Potassium adaptation: 39K NMR evidence for intracellular compartmentalization of K+.? Amer. J. Physiol.: Renal, Fluid and Electrolyte Physiol, 23:F401-F406, 1988.

  77. Miller, R.G., Boska, M.D., Moussavi, R.S., Carson, P.J., Weiner, M.W.? 31P NMR studies of high-energy phosphates and pH in human muscle fatigue: comparison of aerobic and anaerobic exercise.? J. Clin. Invest., 81:1190-1196, 1988.

  78. Karczmar, G.S., Twieg, D.B., Lawry, T.J., Matson, G.B., Weiner, M.W.? Detection of motion using B1 gradients.? Magn. Reson. Med., 7:111-116, 1988.

  79. Weiner, M.W.? The promise of magnetic resonance spectroscopy for medical diagnosis.? Invest. Radiol., 23:253-261, 1988.

  80. Roth, K., Hubesch, B., Meyerhoff, D.J., Naruse, S., Gober, J., Lawry, T., Boska, M., Matson, G., Weiner, M.W.? Non-invasive quantitation of phosphorous metabolites in human tissue by NMR spectroscopy.? J. Mag. Reson., 81:299-311, 1988.

  81. Karczmar, G.S., Shine, N., Lawry, T.J., Weiner, M.W., Matson, G.B.? Improvement of the rotating frame experiment by detection of residual Z magnetization: A 31P MRS study of metabolite levels in a Meth-A sarcoma.? NMR in Biomedicine, 1:159-164, 1988.

  82. Arbeit, J.A., Toy, B.J., Karczmar, G.S., Hubesch, A., Weiner, M.W.? Inhibition of tumor high-energy phosphate metabolism by insulin combined with rhodamine 123.? Surgery, 104:161-170, 1988.

  83. Camacho, S.A., Lanzer, P., Toy, B.J., Gober, J., Botvinick, E., Weiner, M.W.? In vivoalterations of high-energy phosphates and intracellular pH during reversible regional ischemia: a 31P magnetic resonance spectroscopy study.? Amer. Heart J., 116:701-708, 1988.

  84. Matson, G.B., Twieg, D.B., Karczmar, G.S., Lawry, T.J., Gober, J.R., Valenza, M., Boska, M.D., Weiner, M.W.? Image-guided surface coil 31P MRS of human liver, heart, and kidney.? Radiology, 169:541-547, 1988.

  85. Schaefer, S., Gober, J., Valenza, M., Karczmar, G., Matson, G., Camacho, A., Botvinick, E., Massie, B., Weiner, M.W.? Nuclear magnetic resonance imaging guided 31Phosphorous spectroscopy of the human heart.? J. Am. Col. Cardiol., 12:1444-1455, 1988.

  86. Lawry, T.J., Karczmar, G.S., Weiner, M.W., Matson, G.B.? Computer simulation of MRS localization techniques: an analysis of ISIS.? Mag. Reson. Med., 9:299-314, 1989.

  87. Miller, R.G., Carson, P.J., Moussavi, R.S., Boska, M.D., Weiner, M.W.? The use of magnetic resonance spectroscopy to evaluate muscular fatigue and human muscle disease.? Applied Radiology, 18:33-38, 1989.

  88. Karczmar, G.S., Tavares, N.J., Weiner, M.W.? A 31P NMR study of the GI tract: effect of fructose loading and measurement of transverse relaxation times.? Magn. Reson. Med., 9:8-15, 1989.

  89. Schaefer, S., Camacho, S.A., Gober, J.R., Obregon, R.G., DeGroot, M.A., Botvinick, E.H., Massie, B., Weiner, M.W.? Response of myocardial metabolites to graded regional ischemia: 31P NMR spectroscopy of porcine myocardium in vivo.? Circ. Res., 64:968-976, 1989.

  90. Shine, N., Palladino, M.A., Patton, J.S., Deisseroth, A., Karczmar, G.S., Matson, G.B., Weiner, M.W.? Tumor necrosis factor produces rapid depletion of high-energy phosphates in a mouse sarcoma: A 31P NMR study.? Cancer Research, 49:2123-2127, 1989.

  91. Moussavi, R.S., Carson, P.J., Boska, M.D., Weiner, M.W., Miller, R.G.? Nonmetabolic fatigue in exercising human muscle.? Neurology, 39:1222-1226, 1989.

  92. Weiner, M.W.? MR spectroscopic imaging approaches the clinical realm.? Diagnostic Imaging, 11:48-52, 1989.

  93. Baker, A.J., Carson, P.J., Miller, R.G., Weiner, M.W.? Investigations of muscle bioenergetics.? Invest. Radiol., 24:1001-1005, 1989.

  94. Hubesch, B., Sappey-Marinier, D., Hetherington, H., Twieg, D., Weiner, M.W.? 31P MRS studies of human brain.? Investigative Radiology, 24:1039-1042, 1989.

  95. Schaefer, S., Schwartz, G.S., Gober, J.R., Massie, B., Weiner, M.W.? Magnetic resonance spectroscopy: Evaluation of ischemic heart disease.? Investigative Radiology, 24:969-972, 1989.

  96. Karczmar, G.S., Meyerhoff, D.J., Speder, A., Valone, F., Wilkinson, M., Shine, N., Boska, M.D., Weiner, M.W.? Response of tumors to therapy studied by magnetic resonance.? Investigative Radiology, 24:1020-1023, 1989.

  97. Meyerhoff, D.J., Karczmar, G.S., Weiner, M.W.? Abnormalities of the liver evaluated by 31P MRS.? Investigative Radiology, 24:980-984, 1989.

  98. Twieg, D.B., Meyerhoff, D.J., Hubesch, B., Roth, K., Sappey-Marinier, D., Boska, M.D., Gober, J., Schaefer, S., and Weiner, M.W.? Localized phosphorus-31 MRS in humans by spectroscopic imaging.? Magnetic Resonance in Medicine, 12:291-305, 1989.

  99. Weiner, M.W., Hetherington, H.P.? The power of the proton.? Editorial in Radiology, 172:318-320, 1989.

  100. Karczmar, G.S., Kurtz, T., Jalles-Tavares, N., Morris, R.C., Weiner, M.W.? Regulation of hepatic inorganic phosphate and ATP in rats in response to fructose loading: an in vivo31P NMR study.? Biochimica et Biophysica Acta, 1012:121-127, 1989.

  101. Weiner, M.W., Hetherington, H., Hubesch, B., Karczmar, G., Massie, B., Maudsley, A., Meyerhoff, D.J., Sappey-Marinier, D., Schaefer, S., Twieg, D.B., Matson, G.B.? Clinical magnetic resonance spectroscopy of brain, heart, liver, kidney, and cancer: A quantitative approach.? NMR in Biomedicine, 2:290-297, 1989.

  102. Meyerhoff, D.J., Karczmar, G.S., Matson, G.B., Boska, M.D., Weiner, M.W.? Non-invasive quantitation of human liver metabolites using image-guided 31P magnetic resonance spectroscopy.? NMR in Biomedicine, 3:17-22, 1989.

  103. Jadvar, H., Gober, J.R., Schaefer, S., Schwartz, G.S., Weiner, M.W., and Massie, B.? Potential utility of esophageal pacing during cardiac magnetic resonance studies.? American Journal of Electromedicine, 20:134-137, 1989.

  104. Gober, J., Schaefer, S., Camacho, S.A., DeGroot, M., Obregon, R., Botvinick, E., Weiner, M.W., Massie, B.? Epicardial and endocardial localized 31P magnetic resonance spectroscopy: evidence for metabolic heterogeneity during regional ischemia.? Magnetic Resonance in Medicine, 13:204-215, 1990.

  105. Boska, M.D., Hubesch, B., Meyerhoff, D.J., Twieg, D.B., Karczmar, G.S., Matson, G.B., Weiner, M.W.? Comparison of 31P MRS and 1H MRI at 1.5 and 2.0 Tesla.? Magnetic Resonance in Medicine, 13:228-238, 1990.

  106. Boska, M.D., Moussavi, R.S., Carson, P.J., Weiner, M.W., Miller, R.G.? The metabolic basis of recovery after fatiguing exercise of human muscle.? Neurology, 40:240-244, 1990.

  107. Weiner, M.W.? Magnetic resonance spectroscopy and spectroscopic imaging.? Admin. Radiol., 9:32-40, 1990.

  108. Schaefer, S., Schwartz, G.G., Gober, J.R., Wong, A.K., Camacho, S.A., Massie, B., Weiner, M.W.? Relationship between myocardial metabolites and contractile abnormalities during graded regional ischemia: 31P NMR studies of porcine myocardium in vivo.? Journal of Clinical Investigation, 85:706-713, 1990.

  109. Hubesch, B., Sappey-Marinier, D., Roth, K., Meyerhoff, D.J., Matson, G.B., Weiner, M.W.? 31P NMR spectroscopy of normal human brain and brain tumors.? Radiology, 174:401-409, 1990.

  110. Meyerhoff, D.J., Boska, M.D., Thomas, M.A., Weiner, M.W.? Alcoholic liver disease: Quantitative image-guided 31P magnetic resonance spectroscopy.? Radiology, 173:393-400, 1990.

  111. Boska, M.D., Meyerhoff, D.J., Twieg, D.J., Karczmar, G.S., Matson, G.B., Weiner, M.W.? Image-guided 31P magnetic resonance spectroscopy of orthotopic and transplanted human kidneys.? Kidney International, 38:294-300, 1990.

  112. Miller, R.G., Green, A.T., Moussavi, R.S., Carson, P.J., Weiner, M.W.? Excessive muscular fatigue in patients with spastic paraparesis.? Neurology, 40:1271-1274, 1990.

  113. Schaefer, S., Gober, J.R., Schwartz, G.S., Twieg, D.B., Weiner, M.W., Massie, B.? In vivophosphorus-31 spectroscopic imaging in patients with global myocardial disease.? American Journal of Cardiology, 65:1154-1161, 1990.

  114. Shine, N., Xuan, A., Weiner, M.W.? 31P NMR studies of ATP concentrations and Pi-ATP exchange in the rat kidney in vivo:Effects of inhibiting and stimulating renal metabolism.? Magnetic Resonance in Medicine, 14:445-460, 1990.

  115. Thomas, M.A., Narayan, P., Kurhanewicz, J., Jajodia, P., Weiner, M.W.? 1H MR spectroscopy of normal and malignant human prostates in vivo.? Journal of Magnetic Resonance, 87:610-619, 1990.

  116. Maudsley, A.A., Twieg, D.B., Sappey-Marinier, D.S., Hubesch, B., Hugg, J.W., Matson, G.B., Weiner, M.W.? Spin echo 31P spectroscopic imaging in the human brain.? Magnetic Resonance in Medicine, 14:415-422, 1990.

  117. Schwartz, G.S., Schaefer, S., Gober, J.R., Meyerhoff, D.J., Smekal, A., Massie, B., Weiner, M.W.? Myocardial high-energy phosphates in reactive hyperemia.? Am J Physiol, 259:H1190-H1196, 1990.

  118. Weiner, M.W., Jones, R.? New tools for clinicians: magnetic resonance spectroscopic imaging.? Hospimedica, 8:32-46, 1990.

  119. Weiner, M.W., Moussavi, R.S., Baker, A.J., Boska, M.D., Miller, R.G.? Constant relationship between force, phosphate concentration and pH in muscles with differential fatigability.? Neurology, 40:1888-1893, 1990.

  120. Schwartz, G.S., Schaefer, S., Meyerhoff, D.J., Massie, B., Weiner, M.W.? The dynamic relationship between myocardial contractility and energy metabolism during and following brief coronary occlusion in the pig.? Circulation Research, 67:490-500, 1990.

  121. Kurhanewicz, J., Thomas, A., Jajodia, P., Weiner, M., James, T.L., Vigneron, D.B., Narayan, P.? 31P Spectroscopy of the human prostate gland in vivo using a transrectal probe.? Magnetic Resonance in Medicine, 22:404-413, 1991.

  122. Deicken, R., Hubesch, B., Jensen, P., Sappey-Marinier, D., Krell, P., Wisniewiski, A., Vanderburg, D., Parks, R., Fein, G., Weiner, M.W.? Alterations in brain phosphate metabolite concentrations in patients with HIV infection.? Archives of Neurology, 48:203-209, 1991.

  123. Karczmar, G., Meyerhoff, D.J., Boska, M.D., Hubesch, B., Poole, J., Matson, G.B., Valone, F., Weiner, M.W.: 31P MRS study of response of superficial human tumors to therapy.? Radiology, 179:149-153, 1991.

  124. Gober, J.R., Schwartz, G.S., Schaefer, S., Massie, B., Matson, G.B., Weiner, M.W., Karczmar, G.? 31P MRS of myocardial inorganic phosphate using radiofrequency gradient echoes.? Magnetic Resonance in Medicine, 20:171-183, 1991.

  125. Narayan, P., Jajodia, P., Kurhanewicz, J., Thomas, A., MacDonald, J., Hubesch, B., Hedgcock, M., Anderson, C.M., James, T.L., Tanagho, E.A., Weiner, M.W.? Characterization of prostate cancer, benign prostatic hyperplasia and normal prostates using transrectal 31Phosphorus magnetic resonance spectroscopy: a preliminary report.? J Urol, 146:66-74, 1991.

  126. Schwartz, G.S., Schaefer, S., Trocha, S.D., Steinman, S., Gober, J., Massie, B., Weiner, M.W.? Metabolic and functional consequences of blunted myocardial reactive hyperemia.? Amer J Physiol, 261:H892-H900, 1991.

  127. Roth, K., Weiner, M.W.? Determination of cytosolic ADP and AMP concentrations and the free energy of ATP hydrolysis in human muscle and brain tissues with 31P NMR spectroscopy.? Magnetic Resonance in Medicine, 22:505-511, 1991.

  128. Miller, R.G., Carson, P.J., Moussavi, R.S., Green, A.T., Baker, A.J., Weiner, M.W.? Fatigue and myalgia in AIDS patients.? Neurology, 41:1603-1607, 1991.

  129. Lawry, T.J., Weiner, M.W., Matson, G.B.? Computer modeling of surface coil sensitivity.? Magnetic Resonance in Medicine, 16:294-302, 1991.

  130. Minotti, J.R., Christoph, I., Oka, R., Weiner, M.W., Wells, L., Massie, B.M.? Impaired skeletal muscle function in patients with congestive heart failure: Relationship to systemic exercise performance.? Journal of Clinical Investigation, 88:2077-2082, 1991.

  131. Sappey-Marinier, D., Hubesch, B., Matson, G.B., Weiner, M.W.? Decreased phosphorus metabolites and alkalosis in chronic cerebral infarction.? Radiology, 182:29-34, 1992.

  132. Karczmar, G.S., Arbeit, J.A., Toy, B.J., Speder, A., Weiner, M.W.? Selective ATP depletion in a rodent sarcoma by insulin-induced substrate deprivation and inhibition of glycolysis by 2-deoxyglucose.? Cancer Research, 52:71-76, 1992.

  133. Hugg, J.W., Matson, G.B., Twieg, D.B., Maudsley, A.A., Sappey-Marinier, D., and Weiner, M.W.: Phosphorus-31 MR spectroscopic imaging (MRSI) of normal and pathological human brains.? Magnetic Resonance Imaging, 10(2):227-243, 1992.

  134. Schwartz, G.G., Steinman, S., Garcia, J., Greyson, C., Massie, B.M., Weiner, M.W.? Energetics of acute pressure overload of the porcine right ventricle: In vivo 31P NMR spectroscopy.? Journal of Clinical Investigation, 89:909-918, 1992.

  135. Duijn, J.H., Matson, G.B., Maudsley, A.A., and Weiner, M.W.: 3D phase encoding 1H spectroscopic imaging of human brain.? Magnetic Resonance Imaging, 10(2):315-319, 1992.

  136. Sappey-Marinier, D., Deicken, R., Fein, G., Hubesch, B., Van Dyke, C., Dillon, W., Davenport, L., Meyerhoff, D.J., Weiner, M.W.? Alterations in brain phosphorus metabolite concentrations associated with areas of high signal intensity in white matter at MR imaging.? Radiology, 183:247-256, 1992.

  137. Meyerhoff, D.J., Maudsley, A.A., Schaefer, S., and Weiner, M.W.: Phosphorus-31 magnetic resonance metabolite imaging in the human body.? Magnetic Resonance Imaging, 10(2):245-256, 1992.

  138. Fernandez, E.J., Maudsley, A.A., Higuchi, T., and Weiner, M.W.: 1H Spectroscopic Imaging of Rat Brain at 7 Tesla.? Magnetic Resonance in Medicine, 25:107-119, 1992.

  139. Brandes, R., Figueredo, V.M., Camacho, S.A., Massie, B.M., Weiner, M.W.? Suppression of motion artifacts in fluorescence spectroscopy of perfused hearts.? Amer J Physiol, 263:H972-H980, 1992.

  140. Schwartz, G.G., Steinman, S.K., Weiner, M.W., Matson, G.B.? In vivo 31P NMR Spectroscopy of the right ventricle in pigs.? Amer. J. Physiol, 262:H1950-1954, 1992.

  141. Greyson, C., Weiner, M.W. ?Current status of cardiac magnetic resonance spectroscopy.? Current Opinion in Radiology, 4(IV): 48-54, 1992.

  142. Schaefer, S., Schwartz, G.G., Steinman, S.K., Meyerhoff, D.J., Massie, B.M., Weiner, M.W.? Metabolic response of the human heart to inotropic stimulation: in vivo phosphorus-31 studies of normal and cardiomyopathic myocardium.? Magnetic Resonance in Medicine, 25:260-272, 1992.

  143. Sappey-Marinier, D., Calabrese, G., Hetherington, H.P., Fisher, S.N.G., Deicken, R., Fein, G., Weiner, M.W.? Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.? Magnetic Resonance in Medicine, 26:313-327, 1992.

  144. Laxer, K.D., Hubesch, B., Sappey-Marinier, D., Weiner, M.W.? Increased pH and inorganic phosphate in temporal seizure foci: demonstrated by 31P MRS.? Epilepsia, 33:618-623, 1992.

  145. Baker, A.J., Carson, P.J., Green, A.T., Miller, R.G., Weiner, M.W.? The influence of human muscle length on energy transduction studied by 31P NMR.? J. Appl. Physiol, 73:160-165, 1992.

  146. Thomas, M.A., Narayan, P., Kurhanewicz, P., Jajodia, P., James, T.L., Weiner, M.W.? Detection of phosphorus metabolites in human prostates with a transrectal 31P NMR probe.? J. Magn. Reson., 99:377-386, 1992.

  147. Duijn, J.H., Matson, G.B., Maudsley, A.A., Hugg, J.W., and Weiner, M.W.: Human Brain Infarction: Proton MR spectroscopy.? Radiology, 183(3):711-718, 1992.

  148. Meyerhoff, D.J., Karczmar, G.S., Venook, A., Valone, F., Wilkinson, M., Matson, G.B., Weiner, M.W.? Hepatic cancers and their response to chemoembolization therapy: Image-guided 31P MR spectroscopy.? Investigative Radiology, 27:456-464, 1992.

  149. Hugg, J.W., Duijn, J.H., Matson, G.B., Maudsley, A.A., Tsuruda, J.S., Gelinas, D.F., and Weiner, M.W.: Elevated Lactate and Alkalosis in Chronic Human Brain Infarction Observed by 1H and 31P MR Spectroscopic Imaging.? Journal of Cerebral Blood Flow and Metabolism, 12(5):734-744, 1992.

  150. Maudsley, A.A., Lin, E., and Weiner, M.W.: Spectroscopic Imaging Display and Analysis.? Magnetic Resonance Imaging, 10(3):471-485, 1992.

  151. Meyerhoff, D.J., Maudsley, A.A., Husted, C., and Weiner, M.W.: MRSI Detects Biochemical Changes Before Anatomical Changes Become Evident on MRI.? Spectroscopic imaging combines advantages of MRS and MRI.? Magnetic Resonance, Fall:47-52, 1992.

  152. Deicken, R.F., Calabrese, G., Raz, J., Sappey-Marinier, D., Meyerhoff, D., Dillon, W.P., Weiner, M.W., Fein, G.? A 31Phosphorus magnetic resonance spectroscopy study of diazepam does not affect brain phosphorus metabolism.? Biological Psychiatry, 32:628-631, 1992.

  153. Figueredo, V.M, Brandes, R., Weiner, M.W., Massie, B.M., Camacho, S.A.? Cardiac contractile dysfunction during mild coronary flow reductions is due to an altered calcium-pressure relationship in rat hearts.? Journal of Clinical Investigation, 90:1794-1802, 1992.

  154. Sappey-Marinier, D., Bonmartin, A., Weiner, M.W.? Etude des maladies cerebrales par spectroscopie localisee et imagerie spectroscopique RMN.? J Med. Nucl. Biophy., 16:401-411, 1992.

  155. Sappey-Marinier, D., Bonmartin, A., Weiner, M.W.? Metabolic studies of brain by NMR localized spectroscopy and spectroscopic imaging.? Proc Int Conf IEEE, 14:259-263, 1992.

  156. Gordon, L., Levinsohn, D.G., Borowsky, C.D., Manojlovic, R.D., Sessler, D.I., Weiner, M.W., and Baker, A.J.: Improved preservation of skeletal muscle in amputated limbs using pulsatile hypothermic perfusion with University of Wisconsin Solution: A preliminary study.? J. Bone Joint Surg 74:1358-1366, 1992.

  157. Sappey-Marinier, D., Calabrese, G., Fein, G., Hugg, J.W., Biggins, C., and Weiner, M.W.: Effect of photic stimulation on human visual cortex, lactate and phosphates using 1H and 31P magnetic resonance spectroscopy.? J. Cerebral Blood Flow Metabolism 12:584-592, 1992.

  158. Schwartz, G.G., Schaefer, S., Trocha, S.D., Garcia, J., Steinman, S.K., Massie, B, and Weiner, M.W.: Effect of supranormal coronary blood flow on energetics and contractility of the porcine left ventricle.? Cardiovascular Research 26:1001-1006, 1992.?

  159. Fernandez, E.J., Maudsley, A.A., Higuchi, T., and Weiner, M.W.: Three-dimensional 1H spectroscopic imaging of cerebral metabolites in the rat using surface coils.? Magnetic Resonance Imaging, 10(6):965-974, 1992.

  160. Schaefer, S., Schwartz, G.G., Wisneski, J.A., Neese, R.A., Trocha, S.D., Christoph, I., Steinman, S.K., Garcia, J., Massie, B.M., and Weiner, M.W.: Response of high energy phosphate and lactate released during prolonged regional ischemia in vivo.? Circulation 85:342-349, 1992.

  161. Figueredo, V.M., Brandes, R., Weiner, M.W., Massie, B.M., and Camacho, S.A.: Endocardial versus epicardial differences of intracellular free calcium under normal and ischemic conditions in perfused rat hearts.? Circulation Research 72:1082-1090, 1993.

  162. Nagai, Y., Naruse, S., and Weiner, M.W.: Effect of hypoglycemia on changes of brain lactic acid and pH produced by ischemia.? NMR in Biomedicine 6:1-6, 1993.

  163. Calabrese, G., Deicken, R.F., Fein, G., Merrin, E.L., Schoenfeld, F., and Weiner, M.W.: 31Phosphorus magnetic resonance spectroscopy of the temporal lobes in schizophrenia.? Biological Psychiatry 32:26-32, 1993.

  164. DeGroot M., Massie B., Boska M., Gober J.R., Miller, R.G., and Weiner, M.W.: Dissociation of pH from fatigue and relationship of H2PO4- to fatigue in human muscle.? Muscle and Nerve 16:91-98, 1993.

  165. Lara, R.S., Matson, G.B., Hugg, J.W., Maudsley, A.A., and Weiner, M.W.: Quantitation of in vivo phosphorus metabolites in human brain with magnetic resonance spectroscopic imaging (MRSI).? Magnetic Resonance Imaging, 11(2):273-278, 1993.

  166. Meyerhoff, D.J., MacKay, S., Bachman, L., Poole, N., Weiner, M.W., and Fein, G.: Reduced brain n-acetyl aspartate in cognitively impaired human immunodeficiency virus seropositive individuals suggests neuronal loss: In vivo1H magentic resonance spectroscopic imaging.? Neurology 43:509-515, 1993.

  167. Miller, R.G., Moussavi, R.S., Green, A.T., Carson, P.J., and Weiner, M.W.: The distinctive fatigue of rapid repetitive movements.? Neurology 43:755-761, 1993.

  168. Baker, A.J., Longuemare, M.C., Brandes, R., and Weiner, M.W.: Intracellular tetanic calcium signals are reduced in fatigue of whole skeletal muscle.? Amer J Physiol 264:C577-C582, 1993.

  169. Kent-Braun, J.A., Sharma, K.R., Weiner, M.W., Massie, B., and Miller, R.G.: Central basis of muscle fatigue in chronic fatigue syndrome.? Neurology 43:125-131, 1993.

  170. Hugg, J.W., Laxer, K.D., Matson, G.B., Maudsley, A.A., Husted, C.A., and Weiner, M.W.: Lateralization of human focal epilepsy by 31P magnetic resonance spectroscopic imaging.? Neurology, 42(10):2011-2018, 1993.

  171. Camacho, S.A., Figueredo, V.M., Brandes, R., and Weiner, M.W.: Calcium-dependent fluorescence transients and phosphate metabolism during low-flow ischemia in perfused rat hearts.? Amer J Physiol 34:H114-H122, 1993.

  172. Weiner, M.W.: Magnetic resonance spectroscopy and spectroscopic imaging: Studies at San Francisco Veterans Administration Medical Center.? VA Practitioner, pp. 54-63, July 1993.

  173. Kent-Braun, J.A., Miller, R.G., and Weiner, M.W.: Phases of metabolism during progressive exercise to fatigue in human skeletal muscle.? J. Appl. Physiol 75:573-580, 1993.

  174. Baker, A.J., Kostov, K.G., Miller, R.G., and Weiner, M.W.: Slow force recovery after long duration exercise: metabolic and activation factors in muscle fatigue.? Amer J Physiol 74:2294-2300, 1993.

  175. MacKay, S., Meyerhoff, D.J., Dillon, W.P., Weiner, M.W., and Fein, G.: Alteration of brain phospholipid metabolites in cocaine dependent polysubstance abusers.? Biological Psychiatry 34:261-264, 1993.

  176. Higuchi, T., Fernandez, E.J., Maudsley, A.A., and Weiner, M.W.: Mapping of Cerebral Metabolites in Rats by 1H Magnetic Resonance Spectroscopic Imaging: Distribution of Metabolites in Normal Brain and Postmortem Changes.? NMR in Biomedicine, 6:311-317, 1993.

  177. Hugg, J.W., Laxer, K.D., Matson, G.B., Maudsley, A.A., and Weiner, M.W.: Neuron Loss Localizes Human Temporal Lobe Epilepsy by In Vivo Proton Magnetic Resonance Spectroscopic Imaging.? Annals of Neurology, 34(6):788-794, 1993.

  178. Brandes, R., Figueredo, V.M., Camacho, S.A., Baker, A., and Weiner, M.W.: Quantitation of [Ca2+] in whole perfused rat hearts using Indo-1 fluorometry.? Biophysical Journal 65:1973-1982, 1993.

  179. Matson, G.B., Meyerhoff, D.J., Lawry, T.J., Lara, R.S., Duijn, J., Deicken, R.F., and Weiner, M.W.: Use of computer simulations for quantitation of 31P ISIS MRS results.? NMR in Biomedicine 6:215-224, 1993.

  180. Brandes, R., Figueredo, V.M., Camacho, S.A., Baker, A.J., and Weiner, M.W.: Investigation of factors affecting fluorometric quantitation of cytosolic [Ca2+] in perfused hearts.? Biophysical Journal 65:1983-1993, 1993.

  181. Maudsley, A.A., Matson, G.B., Hugg, J.W., and Weiner, M.W.: Display of metabolic information by MR Spectroscopic Imaging.? SPIE, 1887:282-289, 1993.

  182. Hugg, J.W., Laxer, K.D, and Weiner, M.W.: Focal epilepsy localization by magnetic resonance spectroscopic imaging.? Advances in Clinical Neurosciences 3:011-026, 1993.

  183. Massie, B.M., Schwartz, G.G., Garcia, J., Steinman, S., Owens, T., Weiner, M.W., and Wisneski, J.A.: Myocardial metabolism during increased work states: Evidence for "demand ischemia" in the porcine heart in vivo.? Circulation Research 74:64-73, 1994.

  184. Sharma, K.R., Kent-Braun, J.A., Mynhier, M.A., Weiner, M.W., and Miller, R.G.: Excessive muscular fatigue in the post polio syndrome.? Neurology 44:642-646, 1994.

  185. Husted, C.A., Duijn, J.H., Matson, G.B., Maudsley, A.A., and Weiner, M.W.: Molar quantitation of in vivo proton metabolites in human brain with 3D magnetic resonance spectroscopic imaging.? Magnetic Resonance Imaging, 12(4):661-667, 1994.

  186. Graham, S.H., Meyerhoff, D.J., Bayne, L., Sharp, F.R., and Weiner, M.W: Magnetic resonance spectroscopy of n-acetylaspartate in hypoxic-ischemic encephalopathy.? Annals of Neurology 35:490-494, 1994.

  187. Baker, A.J., Brandes, R., Schendel, T.M., Trocha, S.D., Miller, R.G., and Weiner, M.W.: Energy use by contractile and non-contractile processes in skeletal muscle estimated by 31P NMR. Amer J Physiology 266:C825-C831, 1994.

  188. Maudsley, A.A., Wu, Z., Meyerhoff, D.J., and Weiner, M.W.: Automated Processing for Proton Spectroscopic Imaging Using Water Reference Deconvolution.? Magnetic Resonance in Medicine, 31:589-595, 1994.

  189. Maudsley, A.A., Matson, G.B., Hugg, J.W., and Weiner, M.W.: Reduced Phase Encoding in Spectroscopic Imaging.? Magnetic Resonance in Medicine, 31:645-651, 1994.

  190. Vion-Dury, J., Meyerhoff, D.J., Cozzone, P.J., and Weiner, M.W.: What might be the impact on neurology of the analysis of brain metabolism by in vivo magnetic resonance spectroscopy.? J Neurology 241:354-371, 1994.

  191. Ebisu, T., Rooney, W.D., Graham, S.H., Weiner, M.W., and Maudsley, A.A.: N- Acetylaspartate as an In Vivo Marker of Neuronal Viability in Kainate-Induced Status Epilepticus: 1H Magnetic Resonance Spectroscopic Imaging.? Journal of Cerebral Blood Flow and Metabolism, 14(3):373-382, 1994.

  192. Meyerhoff, D.J., MacKay, S., Constans, J-M., Norman, D., VanDyke, C., Fein, G., and Weiner, M.W.: Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging.? Annals of Neurology 36:40-47, 1994.

  193. Garcia, P.A., Laxer, K.D., Van der Grond, J., Hugg, J.W., Matson, G.B., and Weiner, M.W.: 31P magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy.? Annals of Neurology 35:217-221, 1994.

  194. Camacho, S.A., Brandes, R., Figueredo, V.M., and Weiner, M.W.: Ca2+ transient decline and myocardial relaxation are slowed during low-flow ischemia in rat hearts.? Journal of Clinical Investigation 93:951-957, 1994.

  195. Brandes, R., Figueredo, V.M., Camacho, S.A., and Weiner, M.W.: Compensation for changes in tissue light absorption in fluorometry of hypoxic perfused rat hearts.? Amer. J. Physiology 266:H2554-H2567, 1994.

  196. Meyerhoff, D.J., MacKay, S., Poole, H., Dillon, W.P., Weiner, M.W., and Fein, G.: N-acetylaspartate reductions measured by 1H MRSI in cognitively impaired HIV-seropositive individuals: Replication and extension.? Magnetic Resonance Imaging 12:653-659, 1994.

  197. Kent-Braun, J.A., Sharma, K.R., Miller, R.G., and Weiner, M.W.: Post exercise phosphocreatine resynthesis is slowed in multiple sclerosis.? Muscle and Nerve 17:835-841, 1994.

  198. Husted, C.A., Goodin, D.S., Hugg, J.W., Maudsley, A.A., Tsurda, J.S., de Bie, S.H., Fein, G., Matson, G.B., and Weiner, M.W.: Biochemical Alterations in Multiple Sclerosis Lesions and Normal-appearing White Matter Detected by In Vivo 31P and 1H Spectroscopic Imaging.? Annals of Neurology, 36(2):157-165, 1994.

  199. Husted, C.A., Matson, G.B., Adams, D.A., Goodkin, D.S., and Weiner, M.W.: In vivo detection of myelin phospholipids in multiple sclerosis with phosphorus magnetic resonance spectroscopic imaging.? Annals of Neurology 36:239-241, 1994.

  200. Baker, A.J., Carson, P.J., Miller, R.G., and Weiner, M.W.: Metabolic and nonmetabolic components of fatigue monitored with 31P-NMR.? Muscle and Nerve 17:1002-1009, 1994.

  201. Deicken, R.F., Calabrese, G., Merrin, E.L., Meyerhoff, D.J., Dillon, W.P., Weiner, M.W., and Fein, G.: 31Phosphorus magnetic resonance spectroscopy of the frontal and parietal lobes in chronic schizophrenia.? Biological Psychiatry 36:503-510, 1994.

  202. Baker, A.J., Brandes, R., Schreur, J.H.M., Camacho, S.A., and Weiner, M.W.: Protein and acidosis alter calcium-binding and fluorescence spectra of the calcium indicator indo-1.? Biophysical Journal 67:1646-1654, 1994.

  203. Kent-Braun, J.A., Sharma, K.R., Weiner, M.W., and Miller, R.G.: Effects of exercise on muscle activation and metabolism in multiple sclerosis.? Muscle & Nerve 17:1162-1169, 1994.

  204. Schaefer, S., Schwartz, G.S., Steinman, S.K., Garcia, J., Trocha, S.D., Weiner, M.W., and Massie, B.M.: Effects of regional myocardial lidocaine infusion on high-energy phosphates.? J. Mol. Cell. Cardiol. 26:1601-1611, 1994.

  205. Sharma, K.R., Kent-Braun, J.A., Majumdar, S., Huang, Y., Mynhier, M., Weiner, M.W., Miller, R.G. Physiology of fatigue in amyotrophic lateral sclerosis.? Neurology 45:733-740, 1995.

  206. Massie, B.M., Schaefer, S., Garcia, J., McKirnan, M.D., Schwartz, G.G., Wisneski, J.A., Weiner, M.W., and White Francis, C.: Myocardial high energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy.? Circulation 91:1814-1823, 1995.

  207. Garcia, P.A., Laxer, K.D., Grond, J.V.D., Hugg, J.W., Matson, G.B., and Weiner, M.W.: Proton magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy.? Annals of Neurology 37:279-281, 1995.

  208. Deicken, R.F., Merrin, E.L., Floyd, T.C., and Weiner, M.W.: Correlation between left frontal phospholipids and Wisconsin card sort test performance in schizophrenia.? Schizophrenia Research 14:177-181, 1995.

  209. Deicken, R.F., Calabrese, G., Merrin, E.L., Fein, G., and Weiner, M.W.: Altered basal ganglia phosphorous metabolism in chronic schizophrenia.? American Journal of Psychiatry 152:126-129, 1995.

  210. Baker, A.J., Brandes, R., and Weiner, M.W.: Effects of intracellular acidosis on calcium activation, contraction and relaxation of frog skeletal muscle.? Amer. J Physiol 37:C55-C63, 1995.

  211. Miller, R.G., Carson, P.J., Green, A., Baker, A., Moussavi, R.S., Boska, M.D., and Weiner, M.W.: Factors which influence alterations of phosphates and pH in exercising human skeletal muscle: Measurement error, reproducibility, and effects of fasting, carbohydrate loading, and metabolic acidosis.? Muscle and Nerve 18:60-67, 1995.

  212. Deicken, R.F., Weiner, M.W., and Fein, G.: Decreased temporal lobe phosphomonoesters in bipolar disorder.? Journal of Affective Disorders 33:195-199, 1995.

  213. Deicken, R.F., Calabrese, G., Merrin, E.L., Vinogradov, S., Dillon, W.P., Fein, G., and Weiner, M.W.: Asymmetry of temporal lobe phosphorous metabolism in schizophrenia: A 31Phosphorous magnetic resonance spectroscopic imaging study.? Biological Psychiatry 38:279-286, 1995.

  214. Meyerhoff, D.J., MacKay, S., Sappey-Marinier, D., Deicken, R., Calabrese, G., Dillon, W.P., Weiner, M.W., and Fein, G.: Effects of chronic alcohol abuse and HIV infection on brain phosphorus metabolites.? Alcoholism: Clin. Exp. Res 19:685-692, 1995.?

  215. Plesh, O., Meyerhoff, D.J., and Weiner, M.W.: Phosphorus magnetic resonance spectroscopy of human masseter muscle.? Journal of Dental Research 74:338-344, 1995.

  216. Deicken, R.F., Fein, G., and Weiner, M.W.: Abnormal frontal lobe phosphorous metabolism in bipolar disorder.? American Journal of Psychiatry 152:915-918, 1995.

  217. .? Constans, J.M., Meyerhoff, D.J., Gerson, J., MacKay, S., Norman, D., Fein, G., and Weiner, M.W.: H-1 MR spectroscopic imaging of white matter signal hyperintensities: Alzheimer disease and ischemic vascular dementia.? Radiology 197:517-523, 1995.

  218. .? Constans, J.M., Meyerhoff, D.J., Norman, D., Fein, G., and Weiner, M.W.: 1H and 31P magnetic resonance spectroscopic imaging of white matter signal hyperintensities in elderly subjects.? Neuroradiology 37:615-623, 1995.

  219. .? Sharma, K.R., Kent-Braun, J.A., Mynhier, M., Weiner, M.W., and Miller, R.G.: Evidence of an abnormal intramuscular component of muscle fatigue in multiple sclerosis.? Muscle and Nerve 18:1403-1411, 1995.

  220. .? Mancuso, A., Karibe, H., Rooney, W.D., Zarow, G.J., Graham, S.H., Weiner, M.W., and Weinstein, P.R.: Correlation of early reduction in the apparent diffusion coefficient of water with blood flow reduction during middle cerebral artery occlusion in rats.? Magnetic Resonance in Medicine 34:368-377, 1995.

  221. .? Fein, G., Meyerhoff, D.J., and Weiner, M.W.: Magnetic resonance spectroscopy of the brain in alcohol abuse.? Alcohol Health & Research World 19:306-314, 1995.

  222. .???? Di Sclafani, V., Ezekiel, F., Meyerhoff, D.J., MacKay, S., Dillon, W.P., Weiner, M.W., and Fein, G.: Brain atrophy and cognitive function in older abstinent alcoholic men.? Alcoholism: Clinical and Experimental Research 19:1121-1126, 1995.

  223. .? Sappey-Marinier, D., Chileuitt, L., Weiner, M.W., Faden, A.I., and Weinstein, P.R.: Hypoglycemia prevents increase in lactic acidosis during reperfusion after temporary cerebral ischemia in rats.? NMR in Biomedicine 8:171-178, 1995.

  224. .? Higuchi, T., Fernandez, E.J., Maudsley, A.A., Shimizu, H., Weiner, M.W., and Weinstein, P.R.: Mapping of Lactate and N-Acetyl-L-aspartate Predicts Infarction during Acute Focal Ischemia: In Vivo 1H Magnetic Resonance Spectroscopy in Rats.? Neurosurgery, 38(1):121-130, 1996.

  225. .? MacKay, S., Ezekiel, F., Di Sclafani, V., Meyerhoff, D.J., Gerson, J., Norman, D., Fein, G., and Weiner, M.W.: Alzheimer disease and subcortical ischemic vascular dementia: Evaluation by combining MR imaging segmentation and H-1 MR spectroscopic imaging. Radiology 198:537-545, 1996.

  226. .? MacKay, S., Meyerhoff, D.J., Constans, J.M., Norman, D., Fein, G., and Weiner, M.W.: Regional gray and white matter metabolite differences in subjects with AD, with subcortical ischemic vascular dementia, and elderly controls with 1H magnetic resonance spectroscopic imaging.? Archives of Neurology 53:167-174, 1996.

  227. .? Haupt, C.I., Schuff, N., Weiner, M.W., and Maudsley, A.A.: Removal of Lipid Artifacts in 1H Spectroscopic Imaging by Data Extrapolation.? Magnetic Resonance in Medicine, 35:678-687, 1996.

  228. .Meyerhoff, D.J., Weiner, M.W., and Fein, G.: Deep gray matter structures in HIV infection: A 1H MR spectroscopic imaging study.? Amer. J. Neuroradiology 17:973-978, 1996.

  229. .? Kent-Braun, J.A., Sharma, K.R., Miller, R.G., and Weiner, M.W.: Effects of electrically stimulated exercise training on muscle function in multiple sclerosis.? J. Neurol. Rehab 10:143-151, 1996.

  230. .? Hugg, J.W., Maudsley, A.A., Weiner, M.W., and Matson, G.B.: Comparison of k-Space Sampling Schemes for Multidimensional MR Spectroscopic Imaging.? Magnetic Resonance in Medicine, 36:469-473, 1996.

  231. .? Chang, K.C., Schreur, J.H.M., Weiner, M.W, and Camacho, S.A: Impaired Ca2+ handling is an early manifestation of pressure-overload hypertrophy in rat hearts.? Amer. J. Physiology 271:H228-H234, 1996.

  232. .? Meyerhoff, D.J., Rooney, W.D., Tokumitsu, T., and Weiner, M.W.: Evidence of multiple ethanol pools in the brain: An in-vivo proton magnetization transfer study.? Alcoholism: Clinical and Experimental Research 20:1283-1287, 1996.

  233. .? Ebisu, T., Rooney, W.D., Graham, S.H., Mancuso, A., Weiner, M.W., and Maudsley, A.A.: MR Spectroscopic Imaging and Diffusion-Weighted MRI for Early Detection of Kainate Induced Status Epilepticus in the Rat.? Magnetic Resonance in Medicine, 36:821-828, 1996.

  234. Rooney, W.D., Ebisu, T., Mancuso, A., Graham, S., Weiner, M.W., and Maudsley, A.A.: Metabolite 1H relaxation in normal and hyponatremic brain.? Magnetic Resonance in Medicine 35:688-696, 1996.

  235. Meyerhoff, D.J., Weiner, M.W., and Fein, G.: Deep gray matter structures in HIV infection:? 1H MR spectroscopic imaging study.? American J Neuroradiology 17:973-978, 1996.

  236. Shames, D.M., Baker, A.J., Camacho, S.A., and Weiner, M.W.: The calcium-force relationship of frog skeletal muscle: A dynamic model for parameter estimation.? American Journal of Physiology 271(6 Pt.1): C2062-2071, 1996.

  237. Miyamae, M., Camacho, S.A., Weiner, M.W., and Figueredo, V.M.: Attenuation of postischemic reperfusion injury is related to prevention of mitochondrial Ca2+ overload in rat hearts. ???American Journal of Physiology 271:H2145-H2153, 1996.

  238. Ende, G., Laxer, K.D., Knowlton, R.C., Matson, G.B., Schuff, N., Fein, G., and Weiner, M.W.: Temporal lobe epilepsy: Bilateral hippocampal metabolite changes revealed at proton MR spectroscopic imaging.? Radiology 202:809-817, 1997.

  239. Tokumitsu, T., Mancuso, A., Weinstein, P.R., Weiner, M.W., Naruse, S., and Maudsley, A.A.: Metabolic and pathological effects of temporal lobe epilepsy in rat brain detected by proton spectroscopy and imaging.? Brain Research, 744:57-67, 1997.

  240. Higuchi, T., Graham, S.H., Fernandez, E.J., Rooney, W.D., Gaspary, H.L., Weiner, M.W., and Maudsley, A.A.: Effects of Severe Global Ischemia on N-Acetylaspartate and other Metabolites in the Rat Brain.? Magnetic Resonance in Medicine, 37:851-857, 1997.

  241. Garcia, P.A., Laxer, K.D., Van der Grond, J., Hugg, J.W., Matson, G.B., and Weiner, M.W.: Correlation of seizure frequency with N-acetyl-aspartate levels determined by 1H magnetic resonance spectroscopic imaging.? Magnetic Resonance Imaging 15:475-478, 1997.

  242. Rooney, W.D., Goodkin, D.E., Schuff, N., Meyerhoff, D.J., Norman, D., and Weiner, M.W.: 1H MRSI of normal appearing white matter in multiple sclerosis.? Multiple Sclerosis 3:231-237, 1997.

  243. Deicken, R.F., Zhou, L., Corwin, F., Vinogradov, S., and Weiner, M.W.: Decreased left frontal lobe n-acetylaspartate in schizophrenia.? American Journal of Psychiatry 154:688-690, 1997.

  244. Tanabe, J.L., Amend, D., Schuff, N., Di Sclafani, V., Ezekiel, F., Norman, D., Fein, G., and Weiner, M.W.: Tissue segmentation of the brain in Alzheimer?s disease.? American Journal of Neuroradiology 18:115-123, 1997.

  245. Schuff, N., Marmar, C.R., Weiss, D.S., Neylan, T.C., Schoenfeld, F., Fein, G., and Weiner, M.W.: Reduced Hippocampal Volume and N-Acetyl Aspartate in Posttraumatic Stress Disorder.? In: Annals of the New York Academy of Sciences. Supplement on Psychobiology of Posttraumatic Stress Disorders, 821:516-520, 1997.

  246. Miyamae, M., Diamond, I., Weiner, M.W., Camacho, S.A., and Figueredo, V.M.: Regular alcohol consumption mimics cardiac preconditioning by protecting against ischemia-reperfusion injury.? Proc Nat Acad Sci. 94:3235-3239, 1997.

  247. Cruz, C.J., Aminoff, M.J., Meyerhoff, D.J., Graham, S.H., and Weiner, M. W.: Proton MR spectroscopic imaging of the striatum in Parkinson?s disease.? Magnetic Resonance Imaging 15:619-624, 1997.

  248. DiSclafani, V., MacKay, S., Meyerhoff, D.J., Norman, D., Weiner, M.W., and Fein, G.: Brain atrophy in HIV infection is more strongly associated with CDC clinical stage than with cognitive impairment.? Journal of the International Neuropsychological Society 3:276-287, 1997.

  249. Tanabe, J., and Weiner, M.W.: MRI-MRS of the brain in systemic lupus erythematosus: How do we use it to understand causes of clinical signs?? Annals of the New York Academy of Science 823:169-184, 1997.

  250. Baker, A.J., and Weiner, M.W.: Force decline during muscle relaxation promotes calcium release to the cytosol.? American Journal of Physiology 273(Cell Physiology 42):C85-C91, 1997.?

  251. Vermathen, P., Ende, G., Laxer, K.D., Knowlton, R.C., Matson, G.B., and Weiner, M.W.: Hippocampal N-Acetylaspartate in neocortical epilepsy and mesial temporal lobe epilepsy.? Annals of Neurology, 42:194-9, 1997.

  252. Miyamae, M., Camacho, S.A., Rooney, W.D., Modin, G., Zhou, H-Z, Weiner, M.W., and Figueredo, V.M.: Inorganic phosphate and coronary perfusion pressure mediate contractile dysfunction during mild ischemia.? American Journal of Physiology 42:H566-H572, 1997.

  253. Knowlton, R.C., Laxer, K.D., Ende, G., Hawkins, R.A., Wong, S.T.C., Matson, G.B., Rowley, H.A., Fein, G., and Weiner, M.W.: Presurgical multimodality neuroimaging in Electroencephalographic lateralized temporal lobe epilepsy.? Annals of Neurology 42:829-37, 1997.

  254. Kent-Braun, J.A., Ng, A.V., Castro, M., Weiner, M.W., Dudley, G.A., and Miller, R.G.: Strength, skeletal muscle composition and enzyme activity in multiple sclerosis.? Journal of Applied Physiology 83:1998-2004, 1997.

  255. Govindaraju, V., Meyerhoff, D.J., Maudsley, A.A., Vermathen, M., and Weiner, M.W.: Effects of brain membranes on 1H nuclear magnetic resonance signal intensity of ethanol in vitro.? Alcohol & Alcoholism, 32(6):671-681, 1997.

  256. Chang, K.C., Figueredo, V.M., Schreur, J.H.M., Kariya, K.I., Weiner, M.W., Simpson, P.C., and Camacho, S.A.: Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy: Association with increased sarcoplasmic reticulum Ca2+-ATPase and a-myosin heavy chain in rat hearts.? J. Clin. Investigation 100:1742-1749, 1997.

  257. Deicken, R.F., Zhou, L., Schuff, N., and Weiner, M.W.: Proton magnetic resonance spectroscopy of the anterior cingulate region in schizophrenia.? Schizophrenia Research 27:65-71, 1997.

  258. Schuff, N., Amend, D., Ezekiel, F., Steinman, S.K., Tanabe, J., Norman, D., Jagust, W., Kramer, J.H., Mastrianni, J.A., Fein, G., and Weiner, M.W.: Changes of hippocampal N-acetyl aspartate and volume in Alzheimer?s disease: A proton MR spectroscopic imaging and MRI study.? Neurology, 49:1513-21, 1997.

  259. Rooney, W.D., Miller, R.G., Gelinas, D., Schuff, N., Maudsley, A.A., and Weiner, M.W.: Decreased N-acetylaspartate in motor cortex and corticospinal tract in ALS.? Neurology, 50:1800-5, 1998.

  260. Deicken, R.F., Zhou, L., Schuff, N., Fein, G., and Weiner, M.W.: Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy.? Biological Psychiatry 43:483-488, 1998.

  261. Kiefer, A.P., Govindaraju, V., Matson, G.B., Weiner, M.W., and Maudsley, A.A.: Multiple-Echo Proton Spectroscopic Imaging Using Time Domain Parametric Spectral Analysis.? Magnetic Resonance in Medicine, 39:528-538, 1998.

  262. Schuff, N., Amend, D., Meyerhoff, D.J., Tanabe, J., Norman, D., Fein, G., and Weiner, M.W.: Alzheimer?s disease: Quantitative H-1 MR spectroscopic imaging of fronto-parietal brain. Radiology 207:91-102, 1998.

  263. Kent-Braun, J.A., Walker, C.H., Weiner, M.W., and Miller, R.G.: Functional significance of upper and lower motor neuron impairment in amyotrophic lateral sclerosis.? Muscle & Nerve 21:762-768, 1998.

  264. Van der Grond, J., Gerson, J.R., Laxer, K.D., Hugg, J.W., Matson, G.B., and Weiner, M.W.: Regional distribution of interictal 31P metabolic changes in patients with temporal lobe epilepsy.? Epilepsia 39:527-536, 1998.

  265. Tanabe, J.L., Vermathen, M., Miller, R.G., Gelinas, D., Weiner, M.W., and Rooney, W.D.: Reduced MTR in the corticospinal tract and normal T2 in amyotrophic lateral sclerosis.? Magnetic Resonance Imaging 10:1163-1169, 1998.

  266. Goodkin, D.E., Rooney, W.D., Sloan, R., Bacchetti, P., Gee, L., Vermathen, M., Waubant, E., Abundo, M., Majumdar, S., Nelson, S., and Weiner, M.W.: A serial study of new MS lesions and the white matter from which they arise. Neurology 51:1689-1697, 1998.

  267. Schuff, N., Vermathen, P., Maudsley, A.A., and Weiner, M.W.: Proton magnetic resonance spectroscopic imaging in neurodegenerative diseases.? Current Science, 76(6):800-807, 1999.

  268. Tanabe, J.L., Ezekiel, F., Jagust, W.J., Reed, B.R., Norman, D., Schuff, N., Weiner, M.W., Chui, H., and Fein, G.: Magnetization Transfer Ratio of White Matter Hyperintensities in Subcortical Ischemic Vascular Dementia.? American Journal of Neuroradiology, 20:839-844, 1999.

  269. Kwan, L.T., Reed, B.R., Eberling, J.L., Schuff, N., Tanabe, J., Norman, D., Weiner, M.W., and Jagust, W.J.: Effects of Subcortical Cerebral Infarction on Cortical Glucose Metabolism and Cognitive Function.? Archives of Neurology, 56:809-14, 1999.

  270. Meyerhoff, D.J., Bloomer, C., Cardenas, V., Norman, D., Weiner, M.W., and Fein, G.: Elevated subcortical choline metabolites in coginitively and clinically asymptomatic HIV+ patients. Neurology 52:995-1003, 1999.

  271. Schuff, N., Amend, D.L., Knowlton, R., Norman, D., Fein, G., and Weiner, M.W.: Age-related metabolite changes and volume loss in the hippocampus by magnetic resonance spectroscopy and imaging.? Neurobiology of Aging, 20:279-85, 1999.

  272. Meyerhoff, D.J., Bloomer, C., Schuff, N., Ezekiel, F., Norman, D., Clark, W., Weiner, M.W., and Fein, G.: Cortical metabolite alterations in abstinent cocaine and cocaine/alcohol-dependent subjects: proton magnetic resonance spectroscopic imaging.? Addiction Biology 4:405-19, 1999.

  273. Vermathen, P., Laxer, K.D., Matson, G.B., Weiner, M.W.: Hippocampal Structures: Anteroposterior N-acetylaspartate Differences in Patients with Epilepsy and Control Subjects as Shown with Proton MR Spectroscopic Imaging. Radiology, 214:403-10, 2000.

  274. O?Neill, J., Eberling, JL., Schuff, N., Jagust, W., Reed, B., Soto, G., Ezekiel, F., Klein, G., and Weiner, M.W.: Method to Correlate 1H MRSI and 18F DG-PET. Magnetic Resonance in Medicine 43:244-250, 2000.

  275. Capizzano, A.A., Schuff, N., Amend, D.L., Tanabe, J.L., Norman, D., Maudsley, A.A., Jagust, W., Chui, H.C., Fein, G., Segal, M.R., and Weiner, M.W.: Subcortical Ischemic Vascular Dementia: Assessment with Quantitative MR Imaging and 1H MR Spectroscopy.? American Journal of Neuroradiology, 21(4):621-30, 2000.

  276. Suhy, J., Rooney, W.D., Goodkin, D.E., Capizano, A.A., Soher, B.J., Maudsley, A.A., Waubant, E., Anderson, P.B., and Weiner, M.W.: 1H MRSI comparison of white matter and lesions in primary progressive and relapsing-remitting MS. Multiple Sclerosis, 6:148-155, 2000.

  277. Fein, G., Di Sclafani, V., Tanabe, J., Cardenas, V., Weiner, M.W., Jagust, W.J., Reed, B.R., Norman, D., Schuff, N., Kusdra, L., Greenfield, T., Chui, H.? Hippocampal and Cortical Atrophy Predict Dementia in Subcortical Ischemic Vascular Disease.? Neurology, 55:1626-1635, 2000.

  278. Reed, B.R., Eberling, J.L., Mungas, D., Weiner, M.W., and Jagust, W.L.: Memory Failure has Different Mechanisms in Subcortical Stroke and Alzheimer?s disease.? Ann Neurol 48:275-284, 2000.

  279. Soher, B.J., Vermathen, P., Schuff, N., Wiedermann, D., Meyerhoff, D.J., Weiner, M.W., and Maudsley, A.A.: Short TE in vivo 1H MR spectroscopic imaging at 1.5 T: acquisition and automated spectral analysis.? Magnetic Resonance Imaging, 18:1159-1165, 2000.

  280. Schuff, N, Rooney, W.D., Miller, R., Gelinas, D.F., Amend, D.L., Maudsley, A.A., and Weiner, M.W.: Reanalysis of Multislice 1H MRSI in Amyotrophic Lateral Sclerosis.? Magnetic Resonance in Medicine, 45:513-516, 2001.

  281. Weiner, M., DeCarli, C., deLeon, M., Fox, N., Jack C., Scheltens, P., Small, G., Khatchaturian, Z., Peterson, R., and Thal, L.: Neuroimaging for detection, diagnosis and monitoring of Alzheimer?s disease and other dementias: proceedings of the Alzheimer?s Imaging Consortium.? Neurobiology of Aging, 22(2):331-344, 2001.

  282. Schuff, N., Ezekiel, F., Gamst, A.C., Amend, D.L., Capizzano, A.A., Maudsley, A.A., and Weiner, M.W.: Region and Tissue Differences of Metabolites in Normally Aged Brain Using Multislice 1H Magnetic Resonance Spectroscopic Imaging.? Magnetic Resonance in Medicine, 45(5):899-907, 2001.

  283. Capizzano, A.A., Vermathen, P., Laxer, K.D., Ende, G.R., Norman, D., Rowlely, H., Matson, G.B., Maudsley, A.A., Segal, M.R., and Weiner, M.W.: Temporal Lobe Epilepsy: Qualitative Reading of 1HMR Spectroscopic Images for Presurgical Evaluation.? Radiology 218(1):144-151, 2001.

  284. Song, E, Cardenas, V, Ezekiel, F, Weiner, M.W.? Automatic Boundary Modification of Warped Basal Ganglia Template.? Proceedings of SPIE, Vol. 4322, Medical Imaging 2001, San Diego, February 18-22, 2001.

  285. Du, A.T., Schuff, N., Amend, D., Laakso, M.P., Hsu, Y.Y., Jagust, Yaffe, K., Kramer, J.H., Norman, D., Weiner, M.W.: Magnetic Resonance Imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer?s Disease.? Journal of Neurology, Neurosurgery, and Psychiatry 71:441-447, 2001.

  286. Hsu, Y.Y., Du, A.T., Schuff, N., Weiner, M.W.? Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Dementias.? Journal of Geriatric Psychiatry and Neurology 14(3):145-66, 2001.

  287. Kramer, J.H., Reed, B.R., Mungas, D., Weiner, M.W., and Chui, H.C.: Executive dysfunction in subcortical ischaemic vascular disease.? Journal of Neurology, Neurosurgery, and Psychiatry, 72(2):217-20, 2002.

  288. Suhy, J., Miller, R.G., Rule, R., Schuff, N., Licht, J., Dronsky, V., Gelinas, D., Maudsley, A.A., and Weiner, M.W.: Early detection and longitudinal changes in amyotrophic lateral sclerosis by 1H MRSI.? Neurology, 58(6):773-779, 2002.

  289. Schuff, N., Neylan, T.C., Lenoci, M.A., Du, A.T., Weiss, D.S., Marmar, C.R., Weiner, M.W.? Decreased Hippocampal N-Acetylaspartate in the Absence of Atrophy in Posttraumatic Stress Disorder.? Biological Psychiatry, 50(12):952-959, 2001.

  290. Wiedermann, D., Schuff, N., Matson, G.B., Soher, B.J., Du, A.T., Maudsley, A.A., and Weiner, M.W.: Short echo time multislice proton magnetic resonance spectroscopic imaging in human brain: metabolite distributions and reliability.? Magnetic Resonance Imaging, 19(8):1073-1080, 2001.

  291. Mungas, D., Jagust, W.J., Reed, B.R., Kramer, J.H., Weiner, M.W., Schuff, N., Norman, D., Mack, W.J., Willis, L., Chui, H.C.? MRI Predictors of Cognition in Subcortical Ischemic Vascular Disease and Alzheimer?s Disease.? Neurology, 57(2):2229-35, 2001.

  292. Mohr, D.C., Goodkin, D.E., Nelson, S., Cox, D., and Weiner, M.: Moderating Effects of Coping on the Relationship Between Stress and the Development of New Brain Lesions in Multiple Sclerosis.? Psychosomatic Medicine, 64:803-809, 2002.

  293. Suhy, J., Laxer, K.D., Capizzano, A.A., Vermathen, P., Matson, G.B., Barbaro, N.M., Weiner, M.W.: 1H MRSI Predicts Surgical Outcome in MRI-Negative Temporal Lobe Epilepsy.? Neurology, 58(6):821-3, 2002.

  294. Hsu, Y.Y., Schuff, N., Amend, D.L., Du, A-T., Norman, D., Chui, H.C., Jagust, W.J., Weiner, M.W.: Quantitative Magnetic Resonance Imaging Differences Between Alzheimer Disease With and Without Subcortical Lacunes.? Alzheimer Disease and Associated Disorders, 16(2):58-64, 2002.

  295. Schuff, N., Capizzano, A.A., Du, A.T., Amend, D.L., O?Neill, J., Norman, D., Kramer, J., Jagust, W., Miller, B., Wolkowitz, O.M., Yaffe, K., Weiner, M.W.: Selective Reduction of N-acetylaspartate in medial temporal and parietal lobes in AD.? Neurology, 58(6):928-35, 2002.

  296. O?Neill, J., Schuff, N., Marks, W.J. Jr., Feiwell, R., Aminoff, M.J., and Weiner, M.W.: Quantitative 1H Magnetic Resonance Spectroscopy and MRI of Parkinson?s Disease.? Movement Disorders, 17(5):917-27, 2002.

  297. Vermathen, P., Laxer, K.D., Schuff, N., Matson, G.B., and Weiner, M.W.: Evidence of Neuronal Injury Outside the Medial Temporal Lobe in Temporal Lobe Epilepsy: N-Acetylaspartate Concentration Reductions Detected with Multisection Proton MR Spectroscopic Imaging ? Initial Experience.? Radiology, 226(1):195-202, 2003.

  298. Rosen, H.J., Gorno-Tempini, M.L., Goldman, W.P., Perry, R.J., Schuff, N., Weiner, M., Feiwell, R., Kramer, J.H., Miller, B.L.? Patterns of brain atrophy in frontotemporal dementia and semantic dementia.? Neurology 58(2):198-208, 2002.

  299. Capizzano, A.A., Vermathen, P., Laxer, K.D., Matson, G.B., Maudsley, A.A., Soher, B.J., Schuff, N.W., and Weiner, M.W.: Multisection Proton MR Spectroscopy for Mesial Temporal Lobe Epilepsy.? American Journal of Neuroradiology, 23:1359-1368, 2002.

  300. Rosen, H.J., Kramer, J.H., Gorno-Tempini, M.L., Schuff, N., Weiner, M., Miller, B.L.? Patterns of cerebral atrophy in primary progressive aphasia.? American Journal of Geriatric Psychiatry, 10(1):89-97, 2002.

  301. Du, A.T., Schuff, N., Laakso, M.P., Zhu, X.P., Jagust, W.J., Yaffe, K., Kramer, J.H., Miller, B.L., Reed, B.R., Norman, D., Chui, H.C., and Weiner, M.W.: Effects of subcortical ischemic vascular dementia and AD on entorhinal cortex and hippocampus.? Neurology, 58(11):1635-41, 2002.

  302. Vermathen, P., Ende, G., Laxer, K.D., Walker, J.A., Knowlton, R.C., Barbaro, N.M., Matson, G.B., and Weiner, M.W.: Temporal lobectomy for epilepsy: Recovery of the contralateral hippocampus measured by 1H MRS.? Neurology, 59(4):633-36, 2002.

  303. Cardenas, V.A., Du, A.T., Hardin, D., Ezekiel, F., Weber, P., Jagust, W.J., Chui, H.C., Schuff, N., Weiner, M.W.: Comparison of methods for measuring longitudinal brain change in MCI and dementia.? Neurobiology of Aging, 24(4):537-44, Jul-Aug 2003.

  304. Hsu, Y-Y., Schuff, N., Du, A-T., Mark, K., Zhu, X., Hardin, D., and Weiner, M.W.: Comparison of Automated and Manual MRI Volumetry of Hippocampus in Normal Aging and Dementia.? Journal of Magnetic Resonance Imaging, 16(3):305-10, 2002.

  305. Rosen, H.J., Perry, R.J., Murphy, J., Kramer, J.H., Mychack, P., Schuff, N., Weiner, M., Levenson, R.W., and Miller, B.L.: Emotion comprehension in the temporal variant of frontotemporal dementia.? Brain, 125(10): 2286-95, 2002.

  306. Mueller, S.G., Suhy, J., Laxer, K.D., Flenniken, D.L., Axelrad, J., Capizzano, A.A., Weiner, M.W.? Reduced Extrahippocampal NAA in Mesial Temporal Lobe Epilepsy.? Epilepsia, 43(10):1210-6, 2002.

  307. Du, A.T., Schuff, N., Zhu, X.P., Jagust, W.J., Miller, B.L., Reed, B.R., Kramer, J.H., Mungas, D., Yaffe, K., Chui, H.C., and Weiner, M.W.: Atrophy rates of entorhinal cortex in AD and normal aging.? Neurology, 60(3):481-6, 2003.

  308. Neylan, T.C., Schuff, N., Lenoci, M., Yehuda, R., Weiner, M.W., and Marmar, C.R.: Cortisol Levels are Positively Correlated with Hippocampal N-Acetylaspartate.? Biological Psychiatry (In Press)

  309. Boxer, A.L., Rankin, K.P., Miller, B.L., Schuff, N., Weiner, M.W., Gorno-Tempini, M-L., and Rosen, H.J.: Cinguloparietal atrophy distinguishes Alzheimer?s disease from semantic dementia.? Archives of Neurology, 60: 949-956, 2003.

  310. Jahng, G-H., Zhu, X-P., Matson, G.B., and Weiner, M.W.: Improved Perfusion-Weighted MRI by a Novel Double Inversion With Proximal Labeling of Both Tagged and Control Acquisitions.? Magnetic Resonance In Medicine, 49:307-14, 2003.

  311. Weiner, M.W., Albert, M.S., DeCarli, C.S., de Leon, M., Fox, N.C., Jack, C.R., Jr., Jagust, W.J., Reiman, E.M., Scheltens, P., Small, G.W., Soininen, H. and Wahlund, L-O.: Proceedings and Abstracts Second Meeting of the Alzheimer?s Imaging Consortium Stockholm Fairgrounds, Stockholm, Sweden, July 20, 2002.? Neurobiology of Aging, (In Press).

  312. Neylan, T.C., Schuff, N., Lenoci, M., Yehuda, R., Weiner, M.W., and Marmar, C.R.: Cortisol Levels are Positively Correlated with Hippocampal N-Acetylaspartate.? Biological Pyschiatry, (In Press).

  313. Schuff, N., Capizzano, A.A., Du, A.T., Amend, D.L., O?Neill, J., Norman, D., Jagust, W.J., Chui, H.C., Kramer, J.H., Miller, B.L., Yaffe, K., Reed, B., and Weiner, M.W.: Different Patterns of N-acetylaspartate Loss in Ischemic Vascular Dementia and AD.? Neurology, 61(3): 358-364, 2003.

  314. Mueller, S.G., Laxer, K.D., Suhy, J., Lopez, R.C., Flenniken, D.L., and Weiner, M.W.: Spectroscopic Metabolic Abnormalities in mTLE With and Without MRI Evidence for Mesial Temporal Sclerosis Using Hippocampal Short TE MRSI.? Epilepsia, 44(7):977-980, 2003.

  315. Chao, L.L., Meyerhoff, D.J., Cardenas-Nicolson, V.A., Rothlind, J.C., and Weiner, M.W.: Abnormal CNV in Chronic Heavy Drinkers.? Clinical Neurophysiology (In Press).

  316. Boxer, A., Kramer, J.H., Schuff, N., Du, A.T., Weiner, M.W.: Focal right inferotemporal atrophy in AD with disproportionate visual constructive impairment. Nuerology, (In Press).

  317. Schuff, N., Zhu, X., Du, A., Jahng, G.H., Soher, B., Maudsley, A., Weiner M.W.: Magnetic Resonance Spectroscopic Imaging Reconstruction with Deformable Shape-Intensity Models.? Magnetic Resonance in Medicine (In Press).



Manuscripts Submitted

  1. Chao, L.L., Meyerhoff, D.J., Lindgren, J.A., and Weiner, M.W.: The Effects of Chronic Alcohol use on Implicit Memory and Decision-Making Abilities.? Submitted

  2. Du, A.T., Schuff, N., Kramer, J.H., Ganzer, S., Zhu, X.P., Jagust, W.J., Miller, B.L., Reed. B.R., Mungas, D., Yaffe, K., Chui, H.C., and Weiner, M.W.: Higher Atrophy Rate of Entorhinal Cortex than Hippocampus in AD.? Submitted to Neurology.

  3. Kaiser, L.G., Schuff, N., Cashdollar, N., and Weiner, M.W.: Short echo time 1H MR spectroscopy of upper motor neuron regions in normal human brain at 4T.? Submitted to Magnetic Resonance in Medicine.

  4. Lenoci, M., Neylan, T.C., Rothlind, J., Metzler, T.J., Schuff, N., Du, A-T., Franklin, K., Weiss, D.S., Weiner, M.W., and Marmar, C.R.: Attention and Declarative Memory in Posttraumatic Stress Disorder. Submitted to Journal of Traumatic Stress.

  5. Mueller, S.G., Laxer, K.D., Barakos, J.A., Cashdollar, N., Flenniken, D.L., Vermathen, P., Matson, G.B., and Weiner, M.W.: Metabolic Characteristics of Cortical Malformations Causing Epilepsy.? Submitted to Brain.

  6. Mueller, S.G., Laxer, K.D., Barakos, J.A., Cashdollar, N., Flenniken, D.L., Vermathen, P., Matson, G.B., and Weiner, M.W.: Focus Identification in Neocortical Epilepsy with Proton MR Spectroscopic Imaging.? Submitted to Neurology.

  7. Schuff, N., Capizzano, A.A., Du, A.T., Amend, D.L., O?Neill, J., Norman, D., Jagust, J.W., Chui, H., Kramer, Miller, B., Yaffe, K., and Weiner, M.W.: Selective Brain N-acetylaspartate Losses in Vascular Dementia and AD.? Submitted to Neurology.

  8. Vermathen M, Rooney, WD, Goodkin, DE, Weiner, MW.? 1H Magnetic Resonance Spectroscopy of Normal Appearing White Matter in Multiple Sclerosis.? Submitted to Neurology.

  9. Linda L. Chao, Valerie A. Cardenas, Dieter J. Meyerhoff, Johannes C. Rothlind, ?Derek L. Flenniken, Joselyn A. Lindgren, and Michael W. Weiner. ?Evidence of CNS impairment in HIV patients on antiretroviral therapy. Neuroreport.

  10. Laxer, KD, Weiner, MW, Vermathen, P, Matson, GB, Capizzano, AA, Rowley, H, Norman, D, Ende, G, Segal, M, Maudsley, AA.? Qualitative Reading of 1HMRS Images in the Presurgical Evaluation of Temporal Lobe Epilepsy.

  11. Chao, LL, Cardenas, VA, Meyerhoff, DJ, Rothlind, JC, Flenniken, DL, Lindgren, JA, Weiner, MW.? Abnormal Contingent Negative Variation in HIV Patients Receiving Antiretroviral Therapy.?

  12. Tullberg, M, Fletcher, E, DeCarli, C, Mungas, D, Reed, BR, Harvey, J, Weiner, MW, Chui, HC, Jagust, WJ.? Metabolic and cognitive consequences of white matter lesions.?



Abstracts

  1. Weiner, M.W., Hayslett, J.P., Kashgarian, M. and Epstein, F.H.: Accelerated reabsorption in the proximal tubule produced by sodium depletion. Abstracts of IVth International Congress of Nephrology, p.233, 1969. (Presented by M. Weiner at IVth International Congress of Nephrology).

  2. Weinman, E.J., Hayslett, J.P., Weiner, M.W., Kashgarian, M. and Epstein, F.H.: Independent effects of salt depletion and oncotic pressure in the proximal tubule. J. Clin. Invest. 49:101a, 1970. (Presented at the 1970 Annual Meeting of the American Federation Clinical Research).

  3. Weiner, M.W., Torretti, J., Sauer, L.A. and Epstein, F.H.: Function of renal mitochondria in potassium deficiency. Clinical Research 18: 520, 1970.

  4. Weiner, M.W.: Cation transport by kidney mitochondria. Abstracts of the 5th Annual Meeting of the American Society of Nephrology, p.89, 1971.

  5. Weiner, M.W.: Sodium stimulated ATPase activity of kidney mitochondria. J.Lab. Clin. Med. 78:1021, 1971.

  6. Weiner, M.W.: ADP induced reduction of pyridine nucleotides in kidney mitochondria. Federation Proceedings 31:920, 1972.

  7. Weiner, M.W.: Energy dependent sodium transport by kidney mitochondria. Abstracts of Vth International Congress of Nephrology, p.148, 1972. Presented at the Congress.

  8. Manuel, A.R., Beirne, G.J., Wagnild, J.P. and Weiner, M.W.: An effect of sprionolactone on urinary acidification in normal man. Clin. Res. 20: 764, 1972.

  9. Diamond, A.J. and Weiner, M.W.: A quantitative study of renal hydrogen ion secretion and excretion during acute acid loading. Clin. Res. 21: 684, 1973.

  10. Weiner, M.W. and Cunarro, J.A.: Quantitative correlation between the proton-carrying and respiratory-stimulating properties of uncoupling agents using rat liver mitochondria. Federation Proceedings 32:669, 1973. (Presented at Federation Meetings in Atlantic City, N.J. 1973) and Abstracts of Ninth International Congress of Biochemistry, Stockholm, Sweden, July 1973, p.245. (Presented at Congress).

  11. Flygt, T.R. and Weiner, M.W.: Effects of volume-depletion on ATPase, nucleic acids, and compensatory growth of the rat kidney. Abstracts of the 6th Annual Meeting of the American Society of Nephrology, p.36, 1973.

  12. Weiner, M.W.: Effects of chloride on renal Na-K ATPase. Clin. Res. 21:896, 1973.

  13. Manuel, M.A., Cunarro, J.A., and Weiner, M.W.: Action of ethacrynic acid and furosemide on isolated tubules and mitochondria. Clinical Research 22:537A, 1974.

  14. Manuel, M.A. and Weiner, M.W.: Action of ethacrynic acid and furosemide on rat kidney mitochondria. Fed. Proc. 33:1292, 1974. Presented at Meeting of American Soc. Biol. Chem., Minneapolis, Minn. June 1974.

  15. Manuel, M.A., Cunarro, J.A., and Weiner, M.W.: Cellular actions of ethacrynic acid and furosemide. Vll World Congress of Cardiology, Buenos Aires, Argentina, Sept. 1974.

  16. Weiner, M.W., Cunarro, J.A., and Manuel, M.A.: Biochemical mechanisms of ethacrynic acid and furosemide. Proceedings of the International Union of Physiological Sciences. Xl: lll, 1974.

  17. Cunarro, J.A., Manuel, M.A., and Weiner, M.W.: Biochemical actions of diuretics in vivo and in vitro. Circulation 50:136, 1974. American Heart Association, Dallas, Texas, Nov. 1974.

  18. Cunarro, J.A., Manuel, M.A., and Weiner, M.W.: Effects of furosemide on kidney metabolism. Abstracts of the 7th Annual Meeting of the American Society of Nephrology, p.20. Kidney International 6:34A, 1974.

  19. Cunarro, J.A., Johnson, W.A., Uehling, D.T., Updike, S.J., and Weiner, M.W.: Effects of low temperature preservation on metabolite levels of dog renal cortex. Presented at the Kidney Foundation Clinical Dialysis & Transplantation Forum IV:196, 1974 and the Western Dialysis and Transplant Society meetings, San Francisco, 1974.

  20. Cunarro, J.A., Manuel, M.A., and Weiner, M.W.: Mechanism of action of furosemide in vivo and on isolated renal tubules and mitochondria. Clin. Res. 13:102A, 1975. Presented at the meeting of Western Section of A.F.C.R., Carmel, California, February 1975.

  21. Weiner, M.W., Johnson, W.A., Uehling, D.T., and Updike, S.J.: Metabolic consequences of low temperature kidney preservation. Abstracts, International Congress of Nephrology #1020, June 1977.

  22. Weiner, M.W., Cunarro, J.A., and Manuel, M.A.: Biochemical mechanism of furosemide. Abstracts Vlth International Congress of Nephrology #244, June 1977.

  23. Wingert, K.J. and Weiner, M.W.: Acetate dialysance by the Dow-4 hollow fiber artificial kidney. Presented at the Clinical Dialysis and Transplant Forum, 5:15, 1975.

  24. Weiner, M.W.: Mechanism of chloride transport by toad bladder. Abstracts of the 8th Annual Meeting of the American Society of Nephrology. Washington D.C., November 1975, p.96.

  25. Weiner, M.W.: Relationship between chloride, bicarbonate and hydroxyl transport in toad bladder. Clinical Research 24:416A, 1976. Presented at the meeting of the Western Section of A.F.C.R., Carmel, CA, 1976.

  26. Weiner, M.W.: Chloride transport by toad bladder: Exchange with bicarbonate or hydroxyl ion. Federation Proceedings 35:465, 1976. Presented at the FASEB meeting, Anaheim, California, 1976.

  27. Weiner, M.W.: The role of acetate in dialysate for hemodialysis: An investigation using biochemical and radiorespirometric techniques. Proceedings of the 9th Annual Contractors Conference, p.21, 1976. Presented at the 9th Annual Contractors' Conference.

  28. Wingert, K.J. and Weiner, M.W.: Dialysance of acetate by two types of artificial kidneys. Clinical Research 24:150A, February 1976.

  29. Wingert, K.J. and Weiner, M.W.: Acetate dialysance by parallel flow, coil and hollow fiber artificial kidneys. ASAlO 22nd Annual Meeting 5:86, 1976.

  30. Weiner, M.W.: Effects of ethacrynic acid and furosemide on phosphorylation reactions of kidney mitochondria: Inhibition of the adenine nucleotide translocase. Federation Proceedings 35:1558, 1976. Presented at the meeting of the American Society of Biological Chemists, San Francisco, CA. June 1976.

  31. Wingert, K.J. and Weiner, M.W.: Acetate transfer by artificial kidneys in vitro. Abstracts of the Western Dialysis and Transplant Society, p.13, 1976. Presented at the 7th Annual Meeting of the Western Dialysis and Transplant Society. Seattle, Washington, October 1976.

  32. Richards, R.J., Dowling, J.A., Vreman, H.J., Feldman, C.A., and Weiner, M.W.: Acetate levels in human plasma. Abstracts of the Clinical Dialysis and Transplant Forum, p.16, 1976. Presented in Washington, D.C., November 1976.

  33. Weiner, M.W., Vreman, H.J., Richards, R.J., and Feldman, C.A.: The role of acetate in dialysate for hemodialysis. Proceedings of the Tenth Annual Contractors Conference, pp.20-21, 1977. Presented at the Annual Contractors' Conference in Washington D.C., January 1977.

  34. Richards, R.J., Feldman, C.A., Vreman, H.J., and Weiner, M.W.: Acetate metabolism in normal subjects and dialysis patients. Clinical Research 25:446A, 1977.

  35. McTigue, M., Ting, G.O., and Weiner, M.W.: The relationship between sodium transport and oxygen consumption in the perfused rat kidney. Clinical Research 25:442A, 1977.

  36. Winder, C., and Weiner, M.W.: The use of uncoupling agents to distinguish between inhibition of transport or inhibition of metabolism in toad bladders. Clinical Research 25:451A, 1977.